Product Name: AOD 9604 (Advanced Obesity Drug 9604)
Specification: 2mg Lyophilized Powder per Sterile Vial
Manufacturer: GENLABS
Purity: >99% (Verified by HPLC-MS)
Sequence: Tyr-hGH (177-191)
In the cutting-edge field of metabolic and obesity research, targeted molecular tools are paramount. GENLABS is proud to offer researchers a highly refined and pure sample of AOD 9604, a synthetic peptide fragment derived from the C-terminal region (amino acids 177-191) of human Growth Hormone (hGH). This 2mg vial represents a pinnacle of peptide synthesis, providing the scientific community with a specific investigative compound designed to explore fat metabolism pathways without the proliferative or growth-promoting effects associated with the full hGH molecule.
Originally developed and patented by researchers at Metabolic Pharmaceuticals, AOD 9604 was designed to isolate the lipolytic (fat-burning) properties of hGH. For laboratory scientists, this offers a unique and focused tool to dissect the complex mechanisms of adipose tissue regulation, insulin sensitivity, and cellular metabolism. Our commitment at GENLABS is to supply this innovative peptide with uncompromising purity, consistency, and documentation, ensuring your in vitro and preclinical studies are built on a foundation of reliable, high-quality materials.
Molecular Structure and Origin:
AOD 9604 is a modified 15-amino acid sequence (Tyr-hGH 177-191). Its structure is a synthetic replication of the fragment found in natural hGH, but with an additional tyrosine molecule to enhance stability and bioavailability in research models. This deliberate design allows it to interact with specific fat cell receptors while being metabolically "silent" in other hGH-mediated pathways.
Postulated Mechanism of Action for Research Purposes:
Laboratory studies suggest that AOD 9604 operates through a sophisticated and targeted mechanism, distinct from its parent hormone:
Targeted Lipolysis: It is hypothesized to mimic the way hGH interacts with fat cells (adipocytes), specifically promoting the breakdown of stored triglycerides into free fatty acids and glycerol—a process known as lipolysis. Crucially, research indicates it may do so without stimulating the insulin-like growth factor 1 (IGF-1) axis, separating its metabolic activity from growth-promotion.
Inhibition of Lipogenesis: Beyond breaking down fat, early in vitro models propose that AOD 9604 may help inhibit the conversion of carbohydrates into fatty acids (lipogenesis), particularly in the visceral fat depots. This dual-action potential makes it a compound of significant interest for metabolic syndrome research.
Metabolic Rate Modulation: Some preclinical observations point to a potential role in enhancing the metabolic activity of brown adipose tissue (BAT), the "good" fat responsible for thermogenesis, thereby increasing caloric expenditure at a cellular level.
Cartilage and Joint Health Pathways: Emerging, yet preliminary, research in models of tissue repair suggests AOD 9604 may stimulate chondrocyte proliferation and the synthesis of key extracellular matrix components like collagen. This opens ancillary avenues for research into musculoskeletal health and recovery.
It is imperative to note that these mechanisms are derived from scientific literature and are presented for research context. The effects of AOD 9604 in controlled laboratory settings are the primary focus for GENLABS customers.
GENLABS provides AOD 9604 solely for non-human, non-clinical laboratory research. Its properties make it relevant for investigations in several scientific disciplines:
Metabolic Disorder Research: Studying the molecular basis of obesity, hyperlipidemia, and insulin resistance.
Adipocyte Biology: Investigating receptor-level interactions, fat cell differentiation (adipogenesis), and the signaling pathways that control lipolysis and lipogenesis.
Endocrinology & Biochemistry: Exploring the nuanced effects of hormone fragments and their receptor binding profiles.
Sports Science & Physiology (Preclinical): Examining models of body composition, fat reduction, and metabolic efficiency in relevant animal models.
Tissue Repair Studies: Preliminary research into its role in chondrogenesis and cartilage repair mechanisms.
Unmatched Purity & Verification: Every batch of GENLABS AOD 9604 is synthesized to exceed 99% purity, as rigorously verified by High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). Each vial includes a unique Certificate of Analysis (CoA), detailing purity, molecular weight confirmation, and sterility.
Guaranteed Sterility and Stability: The peptide is supplied as a sterile, lyophilized (freeze-dried) powder in a sealed, nitrogen-filled vial. This process ensures long-term stability, prevents oxidation, and maintains the structural integrity of the molecule until reconstitution.
Precision Manufacturing: Our state-of-the-art cGMP-compliant facilities utilize solid-phase peptide synthesis (SPPS) and stringent purification processes, guaranteeing batch-to-batch consistency and accurate dosing for reproducible experimental results.
Research-Grade Focus: GENLABS products are manufactured, packaged, and labeled exclusively for laboratory research use. They are not for human or veterinary consumption, diagnostic use, or any other application outside of a controlled research setting.
Storage: Upon receipt, store the lyophilized vial in a cool, dry place (preferably at or below -20°C). For long-term storage (over 6 months), keeping the product frozen is essential to maintain optimal stability.
Reconstitution: The peptide must be reconstituted with an appropriate sterile solvent (e.g., Bacteriostatic Water). Gently swirl the vial until the powder is fully dissolved. Avoid vigorous shaking to prevent peptide denaturation.
Post-Reconstitution: Once reconstituted, the solution should be aliquoted and stored refrigerated (2-8°C) and used within a short timeframe, or frozen for longer stability. Multiple freeze-thaw cycles should be minimized.
GENLABS AOD 9604 is a chemical for research purposes only. This material is not a drug, dietary supplement, or cosmetic. It is not intended for human consumption, injection, or any form of personal use. It has not been evaluated or approved by the FDA or any other global regulatory body for the diagnosis, treatment, cure, or prevention of any disease or condition.
By purchasing this product, the buyer acknowledges and certifies that they are a qualified researcher affiliated with a recognized institutional or private research facility. The researcher assumes full responsibility for the safe handling, storage, and use of this material in compliance with all applicable local, state, and federal laws and regulations governing laboratory chemicals.
Elevate the precision and reliability of your metabolic research with the gold standard in peptide quality. The GENLABS 2mg vial of AOD 9604 provides a potent, pure, and well-characterized tool to advance your scientific inquiries into fat metabolism and related biological processes.
Navigate complex biological questions with confidence. Add GENLABS AOD 9604 to your research protocol today.
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