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Cambodian Diazepam, also known as Khmer Diazepam, is a medication that belongs to the benzodiazepine class of drugs. Diazepam is a widely used medication primarily prescribed for the treatment of anxiety disorders, muscle spasms, alcohol withdrawal symptoms, and seizures. It is a central nervous system depressant that helps to calm the brain and relax the muscles.

Cambodian Diazepam is similar to the Diazepam available in other countries, but it is specifically produced and marketed in Cambodia. It is important to note that the production and distribution of medications should adhere to the regulations and guidelines set by the respective country's health authorities.

Diazepam works by enhancing the effects of a neurotransmitter in the brain called gamma-aminobutyric acid (GABA). GABA helps to reduce the activity of the brain cells, thus producing a calming effect on the central nervous system. This leads to decreased anxiety, muscle relaxation, and sedation.

Cambodian Diazepam is available in various forms, including tablets and injectable solutions. The dosage prescribed by healthcare professionals depends on the specific condition being treated, the severity of symptoms, and individual patient factors. It is crucial to follow the prescribed dosage and duration as instructed by the healthcare provider to ensure the safe and effective use of the medication.

As with any medication, Cambodian Diazepam may have potential side effects. Common side effects may include drowsiness, dizziness, confusion, impaired coordination, and muscle weakness. These side effects are usually temporary and diminish as the body adjusts to the medication. However, if these side effects persist or worsen, it is important to consult a healthcare professional.

It is worth noting that Diazepam has the potential for abuse and dependence, especially if used for a prolonged period or in high doses. Abrupt discontinuation of the medication may lead to withdrawal symptoms, including anxiety, irritability, insomnia, and seizures. Therefore, it is essential to follow the healthcare provider's instructions for gradual dose reduction when discontinuing the medication.

Before taking Cambodian Diazepam, it is important to inform your healthcare provider about any other medications, supplements, or medical conditions you may have. Diazepam can interact with certain medications, such as other sedatives, antidepressants, anticonvulsants, and opioids, leading to increased sedation or respiratory depression.

In conclusion, Cambodian Diazepam is a benzodiazepine medication prescribed for the treatment of anxiety disorders, muscle spasms, alcohol withdrawal symptoms, and seizures. It works by enhancing the effects of GABA in the brain, leading to a calming effect on the central nervous system. It is important to use this medication as directed by a healthcare professional and be aware of potential side effects and the risk of dependence. Always consult your healthcare provider for personalized advice and guidance regarding the use of Cambodian Diazepam.

VIP 10MG VIAL – GENLABS: The Premier Pharmaceutical-Grade Vasoactive Intestinal Peptide for Elite Research

In the sophisticated landscape of metabolic and cellular research, the integrity of your tools is paramount. Introducing the VIP 10MG VIAL from GENLABS, a pinnacle of peptide engineering designed for the most discerning research professionals. This product represents not just a supply of Vasoactive Intestinal Peptide (VIP), but a commitment to uncompromising purity, precision, and reliability in advanced scientific investigation.

GENLABS has established a formidable reputation by adhering to one core principle: research should never be limited by compound quality. Our VIP 10MG VIAL is the embodiment of this philosophy, providing researchers with a pharmaceutical-grade peptide to explore the vast, complex physiological roles of this crucial neuropeptide with absolute confidence.

What is Vasoactive Intestinal Peptide (VIP)?

Vasoactive Intestinal Peptide is a naturally occurring 28-amino acid polypeptide that functions as a potent neuromodulator and vasodilator. It is a key member of the secretin-glucagon peptide family and is widely distributed throughout the central and peripheral nervous systems, cardiovascular system, and gastrointestinal tract. Its pleiotropic effects make it a subject of intense interest across multiple research domains, including:

• Immunology & Inflammation: VIP exhibits significant immunomodulatory properties, influencing T-cell differentiation, cytokine production, and promoting an anti-inflammatory milieu.

• Pulmonary & Respiratory Research: As a potent bronchodilator and pulmonary vasodilator, VIP's role in airway and vascular smooth muscle relaxation is a critical area of study.

• Neurobiology & Neuroprotection: VIP functions as a neurotrophic factor, supporting neuronal survival, and has been investigated for its potential in models of neural injury and degeneration.

• Cardiovascular Physiology: Its potent vasodilatory effects on coronary and systemic blood vessels make it a compound of interest for hemodynamic studies.

• Metabolic & Endocrine Function: VIP influences pancreatic secretion, glycogenolysis, and lipid metabolism, positioning it as a significant peptide in metabolic pathway analysis.

Unmatched Quality & Precision: The GENLABS Difference

The VIP 10MG VIAL transcends standard offerings. Every step of its production is governed by a rigorous protocol to ensure it meets the exacting standards required for reproducible, high-impact research.

1. Pharmaceutical-Grade Synthesis: Our VIP is synthesized using state-of-the-art Solid-Phase Peptide Synthesis (SPPS) technology. This method allows for precise sequential addition of each L-amino acid, ensuring the correct 28-amino acid sequence is flawlessly constructed.

2. ≥99% Purity Verified by HPLC: The cornerstone of our product's reliability. Each batch of VIP is subjected to rigorous High-Performance Liquid Chromatography (HPLC) analysis. The certificate of analysis (CoA) confirming ≥99% purity is a testament to its exceptional quality, minimizing the risk of research artifacts caused by impurities or truncated sequences.

3. Mass Spectrometry (MS) Confirmation: Beyond purity, identity is everything. We employ Mass Spectrometry to definitively confirm the exact molecular weight of the peptide, providing irrefutable verification that the compound in the vial is authentic, full-length Vasoactive Intestinal Peptide.

4. Sterile Filtration & Lyophilization: The synthesized peptide undergoes sterile filtration (0.22 µm) before being aseptically lyophilized (freeze-dried) in a sterile vial. This process ensures a stable, contaminant-free powder that maintains its structural integrity and bioactivity during long-term storage.

5. Inert Gas Purging & Tamper-Evident Seals: Each vial is purged with an inert gas prior to capping to prevent oxidative degradation. The tamper-evident seal guarantees the product's integrity from our facility to your laboratory.

Technical Specifications & Storage

• Compound: Vasoactive Intestinal Peptide (Human, Rat, Porcine, Canine).

• Sequence: His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2

• Molecular Formula: C₁₄₇H₂₃₈N₄₄O₄₂S

• Molecular Weight: 3325.8 g/mol

• Purity: ≥99% by HPLC

• Form: White, lyophilized powder

• Vial: Sterile, sealed glass vial containing 10mg of pure peptide.

• Storage: For long-term stability, store the VIP 10MG VIAL at or below -20°C in a dedicated freezer upon receipt. For short-term use (under 30 days), storage at 2-8°C is acceptable. Always keep the peptide lyophilized until the moment of reconstitution. Use sterile bacteriostatic water or the appropriate laboratory-grade solvent for reconstitution. Follow aseptic technique to maintain sterility. Once reconstituted, the solution should be refrigerated and used within a short timeframe as indicated by laboratory protocol, as stability in solution is limited.

Intended Application & Research Context

Important Notice: The GENLABS VIP 10MG VIAL is manufactured and sold strictly as a high-purity chemical reagent for in vitro (cell culture) and ex vivo research applications within controlled laboratory settings. It is intended for use by qualified research professionals in institutional, academic, or private R&D laboratories.

This product is designed to facilitate studies in:

• Dose-response assays examining smooth muscle relaxation.

• Cell culture models investigating immunomodulation and cytokine signaling cascades.

• Isolated tissue bath experiments.

• Receptor binding and signaling pathway analysis (VIP primarily acts through VPAC1 and VPAC2 G-protein-coupled receptors).

It is NOT intended for human or veterinary diagnostic, therapeutic, or any other personal use. It is not a drug, supplement, or cosmetic ingredient. Researchers must comply with all applicable local, state, and federal regulations regarding the handling and use of laboratory chemicals.

Why Choose GENLABS for Your Critical Research?

• Transparency: We provide access to batch-specific CoAs (Certificate of Analysis) for every vial, offering full visibility into the analytical data behind your peptide.

• Consistency: Our scaled, cGMP-inspired processes ensure that the VIP you order today is identical in quality to the VIP you will receive in the future, enabling longitudinal research with consistent materials.

• Dedication to Science: GENLABS exists to serve the scientific community. We invest in cutting-edge synthesis and analytical equipment so that you can invest in your research with confidence.

Elevate Your Research with Uncompromised Quality

The complexity of VIP's biological interactions demands a research tool of exceptional fidelity. The VIP 10MG VIAL from GENLABS is precisely that tool—engineered to eliminate variability and empower discovery. When your research explores the frontiers of immunology, neurobiology, or cardiovascular science, trust a peptide that matches your standards.

Order the GENLABS VIP 10MG VIAL today and experience the clarity that only pharmaceutical-grade precision can provide.

Trenbolone acetate is a synthetic anabolic steroid that belongs to the class of drugs known as androgenic steroids. It is derived from the hormone testosterone and was initially developed for veterinary use to promote muscle growth and improve feed efficiency in livestock.

Trenbolone acetate is highly potent and known for its powerful anabolic effects. It is often used by bodybuilders and athletes to enhance muscle mass, strength, and performance. Due to its high androgenic activity, it can also promote fat burning and improve vascularity, giving users a more defined and shredded appearance.

One of the key features of trenbolone acetate is its ability to increase protein synthesis, which leads to accelerated muscle growth and recovery. It also enhances nitrogen retention in the muscles, which is crucial for maintaining an anabolic state and preventing muscle breakdown. This results in increased muscle size, strength, and endurance.

Trenbolone acetate is also known for its ability to boost red blood cell production, leading to improved oxygenation and nutrient delivery to the muscles. This can enhance stamina and endurance during intense workouts or athletic performances.

It is important to note that trenbolone acetate is a strong androgenic steroid with potential side effects. These may include acne, oily skin, increased aggression, hair loss, and potential suppression of natural testosterone production. It can also have negative cardiovascular effects, such as increased blood pressure and cholesterol levels. Due to its potency, it is generally recommended for experienced users who have already completed previous steroid cycles.

Trenbolone acetate is typically administered via intramuscular injection and has a relatively short half-life, requiring frequent dosing. The dosage and cycle length can vary depending on the individual's goals, experience, and tolerance. It is crucial to consult with a healthcare professional or experienced steroid user before starting a trenbolone acetate cycle to ensure proper usage and minimize potential risks.

In conclusion, trenbolone acetate is a powerful anabolic steroid that is commonly used to promote muscle growth, strength, and performance. While it can provide significant benefits, it is crucial to carefully consider the potential side effects and consult with a professional before use.

KAMAJOY-100 Viagra is a revolutionary pharmaceutical product designed to address the common issue of erectile dysfunction (ED) in men. It is a highly potent medication that helps men achieve and sustain firm erections, enhancing their sexual performance and overall satisfaction. With its unique formulation and proven effectiveness, KAMAJOY-100 Viagra has gained significant popularity among men of various age groups.

Key Features:

1. Enhanced Sexual Performance: KAMAJOY-100 Viagra is specifically formulated to improve sexual performance by increasing blood flow to the penis, leading to harder and longer-lasting erections. This allows men to engage in more satisfying and pleasurable sexual experiences.

2. Effective Treatment for Erectile Dysfunction: KAMAJOY-100 Viagra is a trusted solution for men suffering from erectile dysfunction. It works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which allows for better blood circulation to the penile region, resulting in improved erectile function.

3. Quick Onset of Action: This medication is known for its rapid onset of action, typically within 30-60 minutes after ingestion. This allows for greater spontaneity in sexual encounters, providing men with increased confidence and reassurance.

4. Long Duration of Effectiveness: KAMAJOY-100 Viagra provides an extended window of effectiveness, typically lasting up to 4-6 hours. This extended duration allows for multiple sexual encounters within a single dose, eliminating the need for frequent dosage adjustments.

5. Safe and Reliable: KAMAJOY-100 Viagra is a clinically tested and FDA-approved medication, ensuring its safety and reliability. It undergoes rigorous quality control measures to ensure consistent potency and efficacy.

6. Available Dosage Strength: KAMAJOY-100 Viagra comes in a conveniently available dosage strength of 100mg, which is the recommended starting dose for most men. However, it is important to consult with a healthcare professional to determine the appropriate dosage based on individual needs and health conditions.

7. Discreet Packaging: KAMAJOY-100 Viagra is packaged discreetly, respecting the privacy of the user. The product is securely sealed and delivered in a plain packaging, ensuring confidentiality and discretion.

8. Expert Guidance: It is recommended to consult with a healthcare professional before using KAMAJOY-100 Viagra to ensure it is suitable for you. They can provide personalized advice and address any concerns or questions you may have.

Note: KAMAJOY-100 Viagra is a prescription medication, and it should only be used under the guidance of a healthcare professional. It is not recommended for women or individuals under the age of 18.

Disclaimer: This description is intended for informational purposes only. Please consult a healthcare professional for specific medical advice and guidance regarding the use of KAMAJOY-100 Viagra.

NOVORAPID® FLEXPEN® 100 U/mL, 3 mL: Advanced Insulin Therapy for Precise Diabetes Management

In the dynamic landscape of diabetes management, precision, convenience, and reliability are paramount. The NOVORAPID® FLEXPEN® (insulin aspart) represents a sophisticated solution, combining a rapid-acting insulin analogue with one of the world's most trusted and user-friendly delivery systems. Designed for individuals living with diabetes mellitus, this pre-filled insulin pen offers a streamlined approach to managing postprandial blood glucose levels, empowering users with greater flexibility and control over their daily lives.

This comprehensive guide details the features, benefits, and proper use of NOVORAPID® FLEXPEN® 100 U/mL, 3 mL, including the essential pen needles for immediate use.

Understanding NOVORAPID® (Insulin Aspart): The Engine of Rapid Action

At its core, NOVORAPID® contains insulin aspart, a rapid-acting human insulin analogue. It is engineered through recombinant DNA technology to mimic the body's natural insulin response to food, but with a significantly faster onset of action.

• Mechanism & Pharmacokinetics: Unlike regular human insulin, the molecular structure of insulin aspart allows for quicker absorption from the subcutaneous tissue into the bloodstream. This results in a rapid onset of action (typically within 10-20 minutes after injection), a pronounced peak effect (between 1 to 3 hours), and a shorter duration of action (approximately 3 to 5 hours).

• Primary Therapeutic Indication: NOVORAPID® is indicated for the treatment of diabetes mellitus in adults, adolescents, and children aged 1 year and above. Its primary role is to control postprandial (after-meal) blood glucose spikes. It is used alongside a long-acting (basal) insulin regimen or, in some cases, an insulin pump.

• Key Benefits for the User:

  • Mealtime Flexibility: Patients can inject immediately before a meal (0-5 minutes prior) or, when necessary, shortly after starting a meal. This is a significant advantage over regular human insulin, which requires injection 30-45 minutes before eating.

  • Improved Postprandial Control: By closely matching the physiological insulin release triggered by food intake, it helps effectively lower high blood sugar levels after meals.

  • Reduced Hypoglycemia Risk: The shorter duration of action can potentially lower the risk of delayed hypoglycemia compared to regular human insulin, especially between meals and during the night.

The FLEXPEN® Delivery System: A Synergy of Design and Function

The insulin is housed in the innovative FLEXPEN® device, a pre-filled, disposable pen injector. This system is lauded globally for its intuitive design and robust performance, making daily insulin administration more accurate and less burdensome.

Detailed Features and Advantages of the FLEXPEN®:

1. Pre-Filled & Precisely Dosed: Each pen contains 3 mL of NOVORAPID® insulin aspart at a concentration of 100 units per mL (U-100). It is factory-filled, eliminating the need for vial drawing and reducing preparation errors. The large, easy-to-read dose window shows both the selected dose and the remaining insulin.

2. Dose Selector with Audible Clicks: The dial-a-dose selector allows for dosing in 1-unit increments, up to a maximum of 60 units per injection. Each unit adjustment is accompanied by a distinct audible click, providing crucial confirmation for users with visual impairments and ensuring accurate dose setting.

3. Smooth Injection Mechanism: The FLEXPEN® utilizes a simple push-button injection. Once the dose is set and the needle is in place, a press of the thumb-operated button delivers the insulin smoothly. The button requires minimal force, which is beneficial for users with reduced manual dexterity or arthritis.

4. Dose Correction & Safety: Made a mistake while dialing? The dose selector can be easily turned backwards to correct an overdose setting without wasting insulin, as long as the injection button has not been pressed. This "forgiveness" feature prevents inadvertent over-delivery.

5. Consistent & Reliable Delivery: The FLEXPEN® is engineered to deliver the exact dose selected with high accuracy and consistency, dose after dose. Its robust construction helps protect the insulin cartridge from damage.

6. Discreet & Portable: The sleek, pen-like design is discreet and easily fits into a purse, pocket, or dedicated carry case. It facilitates convenient insulin administration at home, work, or while dining out.

Complete Kit: Includes Essential Pen Needles

This offering is a complete starter kit: each box contains 1 x NOVORAPID® FLEXPEN® (3 mL, 100 U/mL) AND a supply of compatible pen needles. This ensures you have everything required to begin treatment immediately. It is critical to use a new, sterile pen needle for every injection to ensure proper insulin flow, maintain injection comfort, and prevent infection, lipodystrophy, and needle blockage.

Administration Guidelines for Optimal Results:

• Route: For subcutaneous injection only. Never inject intravenously or into a muscle.

• Injection Sites: Rotate between recommended sites: the abdomen (fastest absorption), thighs, buttocks, or the back of the upper arms. Injecting into the same spot repeatedly can cause skin thickening or pits (lipodystrophy), affecting insulin absorption.

• Timing: Administer immediately (0-5 minutes) before a meal. If required, it can be given soon after starting a meal.

• Needle Use: Always attach a new pen needle. Perform a "prime" or "air shot" of 1-2 units before each injection to ensure the needle is clear and insulin flows. After injection, keep the button depressed, count to 10 slowly, then remove the needle from the skin to ensure the full dose is delivered.

• Storage: Unused Pens: Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Keep away from the cooling element. In-Use Pen: Once in use, the pen can be kept at room temperature (below 30°C / 86°F) for up to 4 weeks. Do not refrigerate the pen you are currently using. Always protect from excessive heat and direct light.

Important Safety Information & Warnings:

• Hypoglycemia (Low Blood Sugar): The most common adverse reaction. Symptoms include sweating, dizziness, palpitations, hunger, tremor, and confusion. Users must be educated on recognition and treatment (e.g., with glucose tablets).

• Hyperglycemia (High Blood Sugar): Can occur if the dose is insufficient, if the pen is malfunctioning, or due to illness/stress. Symptoms include increased thirst, frequent urination, nausea, and drowsiness.

• Allergic Reactions: Rare but possible. Monitor for localized reactions (redness, swelling at injection site) or systemic reactions (rash, shortness of breath).

• Contraindications: Hypoglycemia and hypersensitivity to insulin aspart or any excipients.

• Drug Interactions: Numerous substances can affect insulin requirements (e.g., corticosteroids, certain antihypertensives, oral antidiabetics, alcohol). Inform your healthcare provider of all medications.

• Pregnancy & Lactation: Consult a physician. Insulin requirements may change during pregnancy and after delivery.

Conclusion: A Trusted Partner in Diabetes Care

The NOVORAPID® FLEXPEN® system is more than just medication; it is a comprehensive tool for modern diabetes therapy. By pairing the rapid, physiological action of insulin aspart with the unparalleled ease, accuracy, and portability of the FLEXPEN® device, it addresses critical needs for both glycemic control and quality of life. It supports a more flexible lifestyle while providing the reliability necessary for effective long-term disease management.

Hygetropin Blacktops 100iu is a synthetic human growth hormone (HGH) that is manufactured by the Chinese pharmaceutical company Hygene Biopharm. It is widely used in the field of medicine for various purposes, including treating growth hormone deficiency, promoting muscle growth, and improving overall body composition.

The Hygetropin Blacktops 100iu comes in the form of lyophilized powder, which is typically reconstituted with sterile water before use. Each vial contains 10iu (international units) of HGH, and the pack includes a total of 10 vials, giving a total of 100iu.

This particular version of Hygetropin is known as "Blacktops" due to the black-colored rubber stopper on the vials. It is important to note that the color of the stopper is simply a distinguishing feature and does not affect the quality or efficacy of the product.

Hygetropin Blacktops 100iu is known for its high purity and potency. It is produced using recombinant DNA technology, where the human growth hormone is synthesized in a laboratory setting using genetically engineered cells. This ensures that the HGH produced is identical to the natural growth hormone present in the human body.

When administered properly, Hygetropin Blacktops 100iu can provide a range of benefits. It stimulates the growth of bones, muscles, and organs, making it an effective treatment for individuals with growth hormone deficiency. Additionally, it can enhance muscle growth and aid in the reduction of body fat, leading to improved body composition. It also has the potential to improve exercise performance, increase energy levels, and support overall well-being.

It is important to note that the use of Hygetropin Blacktops 100iu should be done under the supervision of a qualified healthcare professional. They will determine the appropriate dosage and frequency of administration based on the specific needs of the individual. Like any medication, it may have potential side effects, so it is crucial to follow the prescribed guidelines and consult with a healthcare professional if any adverse reactions occur.

In conclusion, Hygetropin Blacktops 100iu is a synthetic human growth hormone that is widely used for various medical purposes. With its high purity and potency, it offers potential benefits for individuals with growth hormone deficiency, as well as those seeking to enhance muscle growth and improve body composition. However, it is important to use it under medical supervision to ensure safety and effectiveness.

**Pfizer Cabergoline: A Detailed Description**

**Introduction:**
Pfizer Cabergoline is a medication that belongs to the class of drugs known as dopamine receptor agonists. It is primarily used in the treatment of disorders related to the hormone prolactin, such as hyperprolactinemia and prolactin-secreting tumors. Pfizer Cabergoline is marketed under various brand names, including Dostinex and Cabaser, among others.

**Mechanism of Action:**
Pfizer Cabergoline works by stimulating dopamine receptors in the brain. Dopamine is a neurotransmitter that plays a crucial role in regulating various functions in the body. By activating dopamine receptors, Cabergoline inhibits the release of prolactin, a hormone responsible for lactation and other reproductive functions. This helps to reduce the abnormally high levels of prolactin in conditions like hyperprolactinemia.

**Medical Uses:**
1. Hyperprolactinemia: Hyperprolactinemia refers to the condition characterized by elevated levels of prolactin in the blood. Pfizer Cabergoline is commonly prescribed to lower prolactin levels and restore normal hormonal balance. Symptoms of hyperprolactinemia may include irregular menstrual periods, infertility, decreased libido, and breast milk production in non-pregnant or non-lactating individuals.

2. Prolactin-secreting Tumors: Pfizer Cabergoline is also used in the treatment of prolactin-secreting tumors, known as prolactinomas. These tumors are typically benign and occur in the pituitary gland. Cabergoline helps shrink these tumors by reducing the production of prolactin, thereby alleviating symptoms associated with the tumor and preventing complications.

**Dosage and Administration:**
The dosage of Pfizer Cabergoline may vary depending on the condition being treated and individual patient factors. It is typically taken orally in tablet form. The tablets are available in different strengths, and the specific dose is determined by the prescribing healthcare professional. It is important to follow the prescribed dosage and administration instructions carefully.

**Potential Side Effects:**
Like any medication, Pfizer Cabergoline may cause side effects in some individuals. Common side effects may include nausea, dizziness, headache, fatigue, and stomach discomfort. These side effects are usually mild and temporary. However, if any severe or persistent side effects occur, it is important to consult a healthcare professional.

**Precautions and Contraindications:**
Before taking Pfizer Cabergoline, it is essential to inform your healthcare provider about any pre-existing medical conditions, allergies, or medications you are currently taking, including over-the-counter drugs and supplements. Cabergoline should be used with caution in individuals with certain conditions like liver disease, heart valve disorders, or high blood pressure. It is not recommended during pregnancy and breastfeeding, as its safety during these periods has not been established.

**Conclusion:**
Pfizer Cabergoline is a dopamine receptor agonist used in the treatment of hyperprolactinemia and prolactin-secreting tumors. By reducing prolactin levels, it helps restore hormonal balance and alleviate associated symptoms. It is important to follow the prescribed dosage and consult a healthcare professional for any concerns or questions regarding its use.

GenLabs Semaglutide – 5mg/Vial (with Bacteriostatic Water): A Professional-Grade Peptide for Advanced Metabolic Research

Product Name: GenLabs Semaglutide – 5mg/Vial (with Bacteriostatic Water)
CAS Number: 910463-68-2
Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(Boc)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Purity: ≥99% (as determined by HPLC)
Presentation: Lyophilized powder in a sterile, sealed vial. Packaged with 1x 5mg Semaglutide vial and 1x 30ml vial of Bacteriostatic Water (0.9% Benzyl Alcohol).

Introduction: Pioneering Metabolic Research with a Next-Generation GLP-1 Analog

In the rigorous field of metabolic and endocrine research, the quest for high-purity, reliable tools is paramount. GenLabs introduces its professional-grade Semaglutide 5mg/Vial, a meticulously synthesized glucagon-like peptide-1 (GLP-1) receptor agonist, provided as a lyophilized powder for research use only. This product, accompanied by a dedicated vial of bacteriostatic water for reconstitution, is engineered for scientists and research institutions requiring uncompromised quality and consistency in their preclinical studies. Semaglutide’s unique pharmacological profile, characterized by its extended half-life and potent receptor affinity, makes it an indispensable compound for investigating pathways related to glucose homeostasis, appetite regulation, and weight management mechanisms.

GenLabs Semaglutide is manufactured in an ISO-certified facility under strict sterile conditions. Every batch is subjected to rigorous third-party analytical testing, including High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS), to confirm a purity level of 99% or higher and verify peptide sequence accuracy. This commitment to quality ensures researchers can trust the integrity of their compound, eliminating variability and uncertainty from their experimental results.

In-Depth Technical Profile: The Science of Semaglutide

Semaglutide is a long-acting, acylated analog of human GLP-1, a naturally occurring incretin hormone that potentiates glucose-dependent insulin secretion. Its molecular design incorporates key modifications that confer profound stability and extended activity:

• Amino Acid Substitution at Position 8: The substitution of Alanine with the non-proteinogenic AminoIsobutyric Acid (Aib) at position 8 provides exceptional resistance to degradation by the ubiquitous enzyme Dipeptidyl Peptidase-4 (DPP-4). This is the first critical modification that drastically extends the peptide's plasma half-life beyond that of native GLP-1.

• C-18 Fatty Diacid Chain Modification: A strategic attachment of a spacer and a C-18 fatty diacid chain to Lysine at position 26 enables strong, reversible binding to serum albumin. This allows Semaglutide to circulate in the bloodstream for an extended duration while protecting it from renal clearance.

• Potent GLP-1 Receptor Agonism: These structural enhancements not only prolong activity but also enhance affinity for the GLP-1 receptor. The result is a research compound with a pronounced and sustained effect on receptor signaling pathways, making it highly suitable for chronic study models requiring less frequent dosing interventions.

Primary Research Applications & Mechanisms of Action:
In a controlled research setting, GenLabs Semaglutide facilitates the study of:

1. Glucose-Dependent Insulin Secretion: Semaglutide potentiates the secretion of insulin from pancreatic beta-cells in a strictly glucose-concentration-dependent manner. This minimizes the risk of hypoglycemia in research models, a key area of investigation for diabetic pathology.

2. Suppression of Glucagon Secretion: It inhibits the release of glucagon from pancreatic alpha-cells, particularly in hyperglycemic states, thereby reducing hepatic glucose output.

3. Gastric Emptying Delay: Semaglutide slows gastric emptying, which contributes to a moderated postprandial glycemic rise and influences satiety signaling.

4. Central Appetite Regulation: A critical area of research is Semaglutide's action on GLP-1 receptors in the hypothalamus and brainstem. Activation of these central pathways promotes satiety, reduces food intake, and is a focal point for obesity-related research.

5. Beta-Cell Preservation & Function: Preclinical studies utilize Semaglutide to investigate its potential effects on beta-cell proliferation, neogenesis, and the inhibition of apoptosis.

The GenLabs Advantage: Purity, Precision, and Partnership

Choosing GenLabs Semaglutide means selecting a partner dedicated to scientific integrity.

• Unmatched Purity & Verification: Our ≥99% purity guarantee is not a claim but a verified result. Each vial ships with a comprehensive Certificate of Analysis (CoA) detailing HPLC chromatograms and MS data, ensuring complete traceability and transparency.

• Sterile, Lyophilized Presentation: The peptide is supplied as a sterile, lyophilized (freeze-dried) powder in a sealed, neutral glass vial. This format ensures long-term stability when stored correctly and allows for precise, flexible reconstitution to meet various experimental dosing protocols.

• Included Bacteriostatic Water: We provide a complimentary 30ml vial of USP-grade Bacteriostatic Water (containing 0.9% Benzyl Alcohol). This sterile solvent is specifically designed for multi-dose peptide reconstitution, inhibiting bacterial growth for up to 28 days post-puncture when refrigerated, offering convenience and reducing waste.

• Stability & Storage: For optimal long-term stability, store the lyophilized powder at or below -20°C. Once reconstituted with the provided bacteriostatic water, the solution must be stored refrigerated at 2-8°C and used within a defined period as per your laboratory's sterile protocols.

Reconstitution Guidelines for Research Use

Important Note: The following is a general guideline. Researchers must determine the appropriate solvent, concentration, and dosage for their specific in vitro or in vivo study protocols.

1. Aseptic Technique: Perform all steps in a sterile laminar flow hood using sterilized syringes, needles, and personal protective equipment.

2. Reconstitution: Gently inject the desired volume of the provided bacteriostatic water (e.g., 2ml) slowly down the side of the Semaglutide vial to avoid aggressive agitation of the peptide cake.

3. Gentle Mixing: Roll the vial gently between your palms until the lyophilized powder is fully dissolved. Do not shake vigorously, as this can cause denaturation and fibrillation of the peptide.

4. Calculation: Example: Adding 2ml of bacteriostatic water to a 5mg vial yields a concentration of 2.5mg/ml (or 2500 mcg/ml). Researchers can then calculate precise volumetric doses for administration.

Disclaimer & Compliance

CRITICAL NOTICE: GENLABS PRODUCTS ARE INTENDED FOR RESEARCH USE ONLY (RUO).
GenLabs Semaglutide 5mg/Vial is a laboratory chemical for in vitro or preclinical research applications by qualified professionals in controlled settings. It is not for human or veterinary diagnostic, therapeutic, or any other clinical use. It must not be introduced into food, drugs, or household products. The purchaser assumes all responsibility for handling, storage, and disposal in compliance with their institution's guidelines and all applicable local, state, and federal regulations.

By providing a research compound of exceptional purity paired with essential reconstitution solutions, GenLabs empowers the scientific community to push the boundaries of metabolic understanding with confidence and precision. Choose GenLabs Semaglutide for your next research endeavor—where quality is synthesized, and discovery is catalyzed.