GenLabs CJC-1295 (No DAC) – 10mg Lyophilized Peptide for Research Applications
In the evolving landscape of peptide research for metabolic and performance-related studies, specificity and purity are paramount. GenLabs introduces its premium CJC-1295 (No DAC) 10mg vial, a meticulously synthesized and rigorously tested analog of Growth Hormone-Releasing Hormone (GHRH). This product is engineered for the discerning research professional seeking to investigate the profound effects of endogenous growth hormone (GH) pulsatility without the extended half-life modification of its DAC counterpart. Our commitment to excellence ensures you receive a research compound of uncompromising quality, stability, and reliability for your scientific inquiries.
CJC-1295 (No DAC), also widely recognized in research literature as Modified GRF (1-29), is a synthetic peptide comprised of the first 29 amino acids of the endogenous GHRH molecule, stabilized with key modifications for receptor binding and resistance to degradation. Its defining characteristic is the absence of the Drug Affinity Complex (DAC), a feature that critically differentiates its pharmacokinetic profile and research applications from CJC-1295 with DAC.
The compound operates by selectively binding to and activating the GHRH receptors on the anterior pituitary gland. This activation stimulates the synthesis and, more importantly, the natural, pulsatile secretion of endogenous growth hormone. This mimics the body's physiological GH release pattern—sharp, rhythmic pulses primarily occurring during deep sleep, exercise, and fasting. It is this pulsatile secretion that is extensively documented in scientific literature as being crucial for its anabolic, lipolytic, and regenerative effects.
Key Research Parameters of CJC-1295 (No DAC):
Primary Action: Potent agonist of the GHRH receptor.
Effect: Stimulates natural, pulsatile release of endogenous GH.
Half-Life: Approximately 30 minutes, requiring more frequent, timed administration to align with natural secretory windows (e.g., post-training, pre-sleep).
Research Focus: Investigation into the benefits of amplified natural GH pulsatility—enhancing recovery, promoting lean tissue accretion, and improving metabolic markers—without creating constant, supra-physiological GH levels.
Choosing between CJC-1295 with and without DAC is a fundamental decision that shapes the direction of your research.
CJC-1295 with DAC: The DAC moiety binds the peptide to albumin in the bloodstream, creating a "depot effect" that results in a half-life of several days. This leads to a sustained, elevated baseline of GH release, flattening the natural pulsatile rhythm. It is studied for its convenience (less frequent dosing) and continuous exposure.
CJC-1295 No DAC (GenLabs Product): Lacks the albumin-binding complex, resulting in a short half-life. Its research value lies in its ability to amplify the body's existing natural pulses. This approach is central to studies focusing on sleep quality, post-exercise recovery, and mimicking optimal endogenous secretory patterns for body composition and performance.
For researchers aiming to study the effects of enhanced natural physiology without long-term receptor saturation or constant hormonal elevation, the No DAC variant is the precise and logical tool.
GenLabs CJC-1295 (No DAC) is presented as a research chemical for in vitro and in vivo preclinical studies. The following applications are derived from a synthesis of existing peptide science literature:
Recovery & Tissue Repair: By augmenting the natural post-exercise or nocturnal GH surge, research may investigate accelerated repair of musculoskeletal tissues, reduction of recovery time between stressors, and enhanced synthesis of collagen and other structural proteins.
Body Composition & Metabolic Studies: GH is a potent regulator of metabolism. Research may focus on the peptide's role in promoting lipolysis (the mobilization and oxidation of fatty acids for energy) and supporting the development of lean muscle mass by enhancing amino acid uptake and protein synthesis.
Sleep Quality & Nocturnal Physiology: As the largest GH pulse occurs during slow-wave sleep, studies may examine how timed administration influences sleep architecture, overnight recovery processes, and the synergistic relationship between sleep depth and anabolic hormone output.
Bone Density & Connective Tissue Health: GH and its mediator IGF-1 play vital roles in bone mineralization and connective tissue integrity. Research may explore supportive roles in models of tissue strength and skeletal health.
Overall Vitality & Cellular Function: The broad mitogenic and regenerative effects of GH pulses may be studied in the context of cellular turnover, skin health, and overall systemic vitality markers.
Every 10mg vial of GenLabs CJC-1295 (No DAC) is produced under the strictest quality control protocols to ensure the integrity of your research.
High-Purity Synthesis: Manufactured using advanced solid-phase peptide synthesis (SPPS) to achieve a purity standard of >99%, as verified by independent analytical laboratories.
Third-Party Verification: Each batch is subjected to rigorous analysis via High-Performance Liquid Chromatography (HPLC) for purity and Mass Spectrometry (MS) for amino acid sequence confirmation and molecular weight accuracy. Batch-specific Certificates of Analysis (CoA) are available.
Sterile, Lyophilized Format: The peptide is provided as a sterile, lyophilized (freeze-dried) powder in a sealed, nitrogen-flushed vial to ensure maximum stability and longevity.
Strict Quality Assurance: Our facilities adhere to cGMP (current Good Manufacturing Practice) guidelines, guaranteeing consistency, potency, and purity from vial to vial.
Stable & Inert Packaging: Shipped in temperature-controlled packaging with desiccants to protect the hygroscopic peptide from moisture and degradation during transit.
Research Use Only Statement: This product is sold strictly as a research chemical for laboratory and preclinical study purposes. It is not for human or veterinary consumption, nor is it a drug, dietary supplement, or cosmetic. It must be handled only by qualified, licensed research professionals in appropriate controlled settings.
Reconstitution & Storage: To maintain peptide stability, reconstitute with sterile bacteriostatic water or saline specific to your research protocol. Store the lyophilized vial in a cool, dark place (refrigerated at 2-8°C recommended) prior to reconstitution. Once reconstituted, the solution should be kept refrigerated and used within a timeframe dictated by sterility protocols (typically a short window). Always follow aseptic laboratory techniques.
Disclaimer: The information presented here is for educational and research planning purposes. It describes potential investigative pathways based on the known biological function of GHRH analogs. GenLabs does not make any medical or therapeutic claims. Researchers are responsible for complying with all local, state, and federal regulations regarding the acquisition, handling, and use of research peptides.
Elevate your research into growth hormone secretagogues with precision and confidence. Choose GenLabs CJC-1295 (No DAC) 10mg—where scientific rigor meets uncompromising quality.
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