NOVORAPID – FLEXPEN INSULIN – 100 UML 3M

Lilly Humatrope 72iu is a synthetic human growth hormone (HGH) produced by Eli Lilly and Company. It is used for the treatment of growth hormone deficiency in children and adults. This medication comes in the form of a lyophilized powder that is reconstituted with sterile water for injection.

Humatrope contains somatropin, which is identical to the growth hormone naturally produced by the pituitary gland. It stimulates growth, cell reproduction, and regeneration in the body. In children, Humatrope is prescribed to treat growth failure caused by inadequate secretion of growth hormone. In adults, it is used to treat growth hormone deficiency that may occur due to pituitary disease, surgery, or radiation therapy.

The 72iu strength of Humatrope refers to the amount of somatropin present in each vial. It is important to note that the dosage and treatment duration are determined by a healthcare professional based on the individual's specific needs and medical condition.

Humatrope is administered through subcutaneous injection, typically on a daily basis. The injection site should be rotated to prevent lipoatrophy (loss of fat tissue) or hypertrophy (increase in fat tissue). The reconstituted solution should be used immediately or refrigerated for up to 28 days.

As with any medication, Humatrope may cause side effects. Common side effects include injection site reactions, headache, nausea, joint pain, and swelling of the hands and feet. Serious side effects are rare but can include increased intracranial pressure, allergic reactions, and pancreatitis. It is important to monitor for these side effects and report any concerns to a healthcare professional.

Before starting Humatrope treatment, it is crucial to inform your doctor about any medical conditions, allergies, or medications you are taking. This medication may interact with certain drugs, so it is essential to disclose your complete medical history to ensure its safe use.

In conclusion, Lilly Humatrope 72iu is a synthetic human growth hormone used to treat growth hormone deficiency in children and adults. It is administered through subcutaneous injections and should be used under the guidance of a healthcare professional.

Experience the Ancient Wisdom of Ayurveda for Modern, Balanced, and Glowing Skin.

In a world of fleeting beauty trends and complex chemical formulations, true skin wellness often lies in returning to time-honored, nature-derived principles. Vicco Turmeric Skin Cream with Sandalwood Oil is not merely a moisturizer; it is a meticulously crafted Ayurvedic preparation, a testament to over five decades of trusted heritage. This iconic 2.82 oz (80g) jar contains a potent, skin-transforming blend of two of Ayurveda’s most revered botanical treasures: Turmeric (Haridra) and Sandalwood Oil (Chandana). Designed for those seeking clarity, balance, and a naturally radiant complexion, this cream is a daily ritual for purifying, protecting, and nurturing the skin.

Unlocking the Power of Ayurvedic Synergy: Turmeric & Sandalwood

At the heart of this cream is a powerful dual-action formula rooted in Ayurvedic science, which emphasizes balancing the skin's intrinsic energies (doshas), particularly for concerns related to excess heat and impurities.

• Turmeric (Curcuma Longa): Revered for millennia as the "Golden Spice of Life," turmeric is far more than a culinary staple. Its key bioactive compound, curcumin, is a powerhouse antioxidant and natural antiseptic with remarkable soothing properties. In Ayurveda, turmeric is celebrated for its ability to purify the blood, reduce inflammation, and promote healing. When applied topically, it works diligently to:

  • Clarify the Skin: Gently helps reduce the appearance of blemishes, uneven skin tone, and post-blemish marks by targeting impurities at the surface.

  • Soothe & Comfort: Calms skin that is prone to redness and irritation, providing a comforting sensation.

  • Illuminate Complexion: Its natural properties help fade dullness, promoting a clearer, more even-toned, and luminous glow.

  • Protect: Acts as a shield against environmental aggressors with its antioxidant strength.

• Sandalwood Oil (Santalum Album): Known as one of the world's most precious essential oils, sandalwood holds a sacred place in Ayurveda for its profoundly calming, cooling, and spiritually elevating qualities. Its integration into this cream provides a multi-dimensional benefit:

  • Deep Cooling Action: Inherently cooling, it perfectly complements turmeric by helping to balance skin temperature and soothe sensations of heat—a common concern for skin experiencing imbalance.

  • Astringent & Toning: Gently tightens pores and refines skin texture, promoting a smoother, more refined appearance.

  • Aromatic Therapy: Its distinctive, woody, and serene fragrance is instantly grounding. It calms the mind, reduces stress, and elevates the simple act of skincare into a moment of mindful ritual.

Beyond the Stars: A Holistic Botanical Formulation

While turmeric and sandalwood are the celebrated heroes, Vicco’s formula is a complete symphony of supportive Ayurvedic botanicals and natural ingredients:

• Vasaka (Malabar Nut): Known for its cleansing and healing virtues.

• Licorice: A natural brightening agent that helps even out skin tone.

• Foaming Bark: Provides a gentle cleansing effect within the cream.

• Mysore Sandalwood Oil: Specially sourced for its guaranteed purity and efficacy.

• Turmeric Powder & Turmeric Oil: Delivering the benefits of turmeric in multiple, potent forms for a layered effect.

• No Added Colors or Synthetic Fragrances: The cream’s warm, earthy beige hue and soothing scent come directly from its natural ingredients, making it suitable for even the most sensitive skin types.

Who is Vicco Turmeric Cream For? A Solution for Multiple Skin Goals

This versatile cream is a skincare staple for a diverse range of individuals:

• Those with Oily, Combination, or Blemish-Prone Skin: Its oil-free, non-comedogenic formula helps manage excess sebum, clarifies pores, and soothes active blemishes without over-drying.

• Individuals Seeking Brighter, More Even Skin Tone: A natural choice for addressing dullness, dark spots, and post-acne hyperpigmentation for a more uniform complexion.

• Anyone with Sensitive or Reactive Skin: Free from harsh chemicals, parabens, and artificial colors, its gentle, natural formula calms and comforts.

• Men & Women as an After-Shave or Post-Depilatory Soother: The cooling sandalwood and soothing turmeric provide exceptional relief from razor burn and minor skin irritation.

• Wellness Enthusiasts: For those who prioritize holistic, plant-based products rooted in authentic tradition and conscious ingredient sourcing.

• As a Targeted Spot Treatment: A small dab applied directly to areas of concern can provide concentrated overnight clarifying action.

How to Integrate into Your Daily Ritual: Usage Guidelines

For optimal results, incorporate Vicco Turmeric Cream into both your morning and evening routines:

1. Cleanse: Start with a gentle cleanser to remove impurities.

2. Tone (Optional): Apply your preferred toner.

3. Apply Vicco Turmeric Cream: Take a small, pea-sized amount. Emulsify between your fingertips and apply evenly over the entire face and neck, using gentle, upward strokes. Its lightweight texture absorbs readily without leaving a heavy or greasy residue—only a matte, velvety finish.

4. Follow with Sunscreen (AM): While the cream offers antioxidant protection, during the day, always follow with a broad-spectrum sunscreen, as turmeric can make skin more photosensitive.
   Note: The presence of natural turmeric may impart a subtle, warm tint on very fair skin, which blends in naturally. For a deeper treatment, it can also be used as a 10-15 minute mask before rinsing.

The Vicco Heritage: Trust Built Over Generations

Vicco Laboratories has been a pioneer in bringing authentic Ayurveda to households since 1952. Their commitment is not to trends, but to the uncompromising quality, purity, and efficacy of their preparations. Every jar of Turmeric Skin Cream is produced under strict quality controls, ensuring that the ancient wisdom encapsulated within delivers consistent, visible results. This is a product passed down through generations, a staple in South Asian skincare cabinets now embraced globally for its undeniable effectiveness.

Embrace Your Natural Glow. The Time for Pure, Ayurvedic Care is Now.

Vicco Turmeric Skin Cream with Sandalwood Oil is more than a solution; it is a return to balance. It represents a conscious choice to treat your skin with the respect it deserves, using ingredients that nurture from the surface to the sensory level. It promises not overnight miracles, but the steady, reliable improvement that comes from consistent, natural care.

Genlabs BPC-157 – 20mg/Vial: The Premier Systemic Repair Peptide for Advanced Research

Product Name: Genlabs BPC-157 – 20mg/Vial (with Bacteriostatic Water)
SKU: GL-BPC157-20
Catalog: Research Peptides

Introduction: Redefining the Frontier of Systemic Recovery Research

In the rigorous field of research peptides, few compounds have generated as much scientific interest for their broad-spectrum systemic properties as BPC-157. Genlabs, a name synonymous with precision and purity, presents its flagship BPC-157 – 20mg/Vial, meticulously synthesized and paired with sterile Bacteriostatic Water. This high-concentration formulation is designed for the discerning researcher seeking to investigate the remarkable regenerative and protective mechanisms of this stable peptide fragment. Our 20mg vial offers exceptional value and flexibility, allowing for precise dosing regimens in controlled experimental settings focused on musculoskeletal, gastrointestinal, and systemic inflammatory responses.

Genlabs’ commitment to excellence ensures every batch is verified for >99% purity, is sterile-filtered, and undergoes independent third-party analysis (COA available). This product is presented strictly for in-vitro and research applications in laboratory settings.

What is BPC-157? A Scientific Overview

BPC-157 (Body Protection Compound-157) is a synthetic peptide sequence comprising 15 amino acids, derived from a protective protein found in human gastric juice. Unlike larger, more fragile proteins, this pentadecapeptide is renowned for its exceptional stability and systemic effects in research models. It is not a growth hormone or a steroid; rather, it is characterized as a "protective modulator" with a unique mechanism of action centered on promoting cellular survival, angiogenesis (formation of new blood vessels), and tissue repair across a wide range of systems.

Its proposed research profile suggests it operates through several key pathways: promoting VEGF (Vascular Endothelial Growth Factor) expression for improved blood flow to injured sites, modulating inflammatory cytokine responses to maintain a balanced healing environment, and stimulating the synthesis of collagen and other structural proteins. This multi-modal approach has made BPC-157 a subject of extensive preclinical investigation.

Genlabs BPC-157 – 20mg: Key Features & Advantages

1. Uncompromising Purity & Verification: Each batch is synthesized using state-of-the-art solid-phase peptide synthesis (SPPS) and undergoes rigorous HPLC (High-Performance Liquid Chromatography) and MS (Mass Spectrometry) testing. The certificate of analysis confirms a purity level of >99%, ensuring your research is not compromised by contaminants or filler peptides.

2. Optimal Concentration & Format: The 20mg per vial format is ideal for extended research protocols. This substantial quantity provides researchers with ample material for longitudinal studies or higher-dose investigations without frequent replenishment, ensuring consistency across the experimental timeline.

3. Included Bacteriostatic Water: Each order includes a separate vial of sterile, USP-grade 0.9% Bacteriostatic Sodium Chloride Injection (containing 0.9% benzyl alcohol). This eliminates the need for separate sourcing and guarantees compatibility, making the reconstitution process seamless and aseptic.

4. Lyophilized for Maximum Stability: The peptide is provided in a stable, freeze-dried (lyophilized) powder form within a sterile glass vial. This preservation method ensures long-term stability when stored correctly, protecting the integrity of the molecular structure until reconstitution.

5. Sterile-Filtered & Prepared in a cGMP-Compliant Facility: Our manufacturing process adheres to current Good Manufacturing Practices (cGMP). The solution is sterile-filtered through a 0.22-micron filter before lyophilization, a critical step to ensure sterility and researcher safety.

6. Comprehensive Third-Party Testing: Beyond in-house QC, samples from every lot are sent to an independent, ISO-certified laboratory for confirmatory analysis. The resulting Certificate of Analysis (COA) is transparently available, providing verified data on purity, weight, and absence of endotoxins or microbial growth.

Primary Research Applications & Investigative Pathways

*Disclaimer: The following are well-documented areas of scientific inquiry based on preclinical studies. Genlabs BPC-157 is sold for laboratory research use only.*

• Musculoskeletal & Tendon-Ligament Repair: A primary focus of BPC-157 research is its potential to accelerate the healing of various connective tissues. Studies have investigated its effects on models of tendon-to-bone healing, muscle fiber regeneration, and ligament repair. Its proposed angiogenic and collagen-stimulating properties are of particular interest in this domain.

• Gastrointestinal System Protection & Healing: Given its origin, significant research explores BPC-157's protective effects on the GI tract. Investigations include models of gastric ulcers, inflammatory bowel conditions, and intestinal anastomosis healing. It is studied for its potential to promote mucosal integrity and modulate local blood flow.

• Systemic Anti-Inflammatory Modulation: Researchers examine BPC-157's role in influencing systemic inflammatory responses. Its interaction with key inflammatory pathways (e.g., TNF-alpha, COX-2) is a subject of interest for creating a balanced cellular environment conducive to recovery.

• Organ Protection & Support: Emerging research vectors include investigating BPC-157's potential protective effects on the liver (in toxin-exposed models), heart (in ischemia-reperfusion injury models), and nervous system.

• Angiogenesis & Wound Healing: The peptide's strong association with promoting VEGF-driven angiogenesis places it at the center of wound healing research, particularly in models of impaired healing or compromised blood supply.

Reconstitution, Storage, and Handling Protocol

Storage (Lyophilized Powder): Store immediately upon receipt in a freezer at -20°C or below. For long-term storage (over 6 months), a temperature of -80°C is recommended. Keep the vial in its original desiccated state and protected from light.

Reconstitution:

1. Gently swirl the vial of Bacteriostatic Water to mix.

2. Using aseptic technique, draw the desired volume of bacteriostatic water into a sterile syringe.

3. Slowly inject the water down the side of the vial containing the BPC-157 lyophilized powder. Avoid directing a high-pressure stream directly onto the powder.

4. Gently swirl or roll the vial until the powder is fully dissolved. Do not shake vigorously, as this can cause denaturation of the peptide.

Storage (Reconstituted Solution): Once reconstituted with bacteriostatic water (which contains a preservative), the solution should be refrigerated at 2-8°C (36-46°F). Under these conditions, stability is typically maintained for up to 21 days. For optimal potency, many researchers prefer to use the solution within 7-10 days. Aliquotting into smaller, sterile vials can minimize repeated freeze-thaw cycles if freezing the reconstituted solution is necessary.

Why Choose Genlabs for Your Peptide Research?

Genlabs stands apart in the research peptide industry through an unwavering dedication to scientific integrity:

• Transparency is Paramount: We provide batch-specific, third-party COAs, not generic datasheets.

• Purity-First Philosophy: Our >99% purity standard is non-negotiable, ensuring reliable and reproducible research outcomes.

• Researcher-Centric Formatting: The inclusion of bacteriostatic water and high-concentration vials is designed for convenience and experimental flexibility.

• Compliance & Ethics: We operate with strict adherence to legal and ethical guidelines, supplying products exclusively to verified research institutions and qualified professionals for laboratory investigation.

Product Specifications:

• Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

• Molecular Formula: C₆₂H₉₈N₁₆O₂₂

• Molecular Weight: 1419.5 g/mol

• Purity: >99% (by HPLC)

• Form: Lyophilized white powder

• Packaging: 20mg peptide in sterile glass vial + 2ml bacteriostatic water (0.9% BA) in separate vial.

Professional-Grade Muscle Recomposition and Performance Amplification

GENLABS TRENBOLONE ENANTHATE 180mg/mL represents the pinnacle of anabolic engineering for the experienced performance athlete. This is not a foundational or beginner compound; it is a highly sophisticated and potent androgen designed for one primary purpose: to forge a physique of exceptional density, striated muscle, and hardened, lean mass where other anabolics reach their limit. Operating at a concentrated 180mg per milliliter, this formulation delivers the powerful trenbolone hormone via the enanthate ester, balancing potent effects with a manageable injection frequency for seasoned users.

Understanding this product requires moving beyond basic anabolic concepts. Trenbolone Enanthate is the engineered successor to Trenbolone Acetate, featuring a longer carbon chain (enanthate ester) that allows for a slower release from the injection site into the bloodstream. This translates to a more stable blood plasma level, reducing the peak-and-trough effect and requiring less frequent injections—typically twice per week—compared to its acetate counterpart. The GENLABS 180mg/mL concentration further optimizes this delivery, providing a high milligram-per-injection yield, minimizing injection volume, and offering advanced users greater control over precise dosing within a cycle.

Mechanism of Action: A Symphony of Anabolic Efficiency

Trenbolone’s legendary status is rooted in its unique and multifaceted mechanism of action, which operates on several physiological levels simultaneously:

1. Extreme Androgen Receptor Affinity: Trenbolone exhibits an affinity for the androgen receptor (AR) that is significantly higher than that of testosterone. This powerful binding dramatically upregulates nitrogen retention and protein synthesis at the cellular level, creating a profoundly anabolic environment where muscle tissue repair and growth are aggressively prioritized.

2. Progesterone Receptor Agonism: Unlike many anabolic steroids, trenbolone also acts as an agonist at the progesterone receptor. This action, while requiring careful management with other compounds, can contribute to further inhibition of cortisol (the primary catabolic hormone) and may synergistically enhance the anabolic effects via different pathways. This dual-receptor activity is a key factor in its unparalleled ability to promote lean tissue accretion.

3. Nutrient Partitioning and Metabolic Enhancement: Perhaps one of Trenbolone Enanthate’s most valued effects is its ability to drastically improve nutrient partitioning. This means a greater percentage of consumed calories is shuttled directly toward muscle tissue as usable energy and building blocks, while simultaneously being diverted away from adipose (fat) storage. Users experience a noticeable increase in basal metabolic rate, vascularity, and a distinct "hardened" appearance as subcutaneous water and fat diminish.

4. IGF-1 Upregulation: Trenbolone potently increases levels of Insulin-like Growth Factor 1 (IGF-1) within muscle tissues. IGF-1 is a critical mediator of muscle hypertrophy, satellite cell activation, and overall recovery, amplifying the direct anabolic signaling of the compound itself.

Primary Applications and Cycle Objectives

GENLABS TRENBOLONE ENANTHATE 180mg/mL is strategically deployed within specific, goal-oriented phases:

• Ultimate Cutting and Competition Prep: This is its most renowned application. During a caloric deficit, its powerful anti-catabolic and nutrient-partitioning properties act as a shield for hard-earned muscle mass. It promotes dramatic fat loss, extreme muscular definition, graininess, and that coveted "3D" look on stage, while preserving full muscle bellies.

• Lean Mass and Recomposition Cycles: For athletes seeking quality over sheer bulk, Trenbolone Enanthate is unparalleled. When paired with a moderate caloric surplus or even maintenance calories, it can drive significant increases in lean, dense, water-free muscle tissue, often simultaneously reducing body fat percentage—a feat few compounds can achieve.

• Performance and Strength Phases: The dramatic increase in protein synthesis and neural efficiency often translates into rapid and substantial gains in raw strength and power output, benefiting strength athletes and those in speed-strength sports.

User Protocol and Administration (For Educational Purposes)

This product is strictly for experienced athletes with a comprehensive understanding of advanced anabolic cycles. Typical dosing for experienced individuals ranges from 200mg to 400mg per week, often divided into two injections (e.g., Monday/Thursday). Due to its concentration (180mg/mL), careful calculation is required. It is crucially important to note that Trenbolone Enanthate is not aromatizable—it does not convert to estrogen via the aromatase enzyme. Therefore, standard aromatase inhibitors (AIs) like Anastrozole are ineffective against its potential side effects.

Cycles are typically 8-12 weeks in length. Trenbolone Enanthate is never used as a standalone "monotherapy." It must be combined with a testosterone base (e.g., Testosterone Enanthate or Cypionate) to provide the essential physiological testosterone that trenbolone suppresses. A common and effective stack is "Test and Tren," with doses often adjusted so that testosterone is equal to or slightly higher than the trenbolone dose for optimal balance and well-being.

Critical Side Effect Profile and Risk Mitigation

Respect for this compound is non-negotiable. Its potency is matched by its potential for significant side effects, which must be proactively managed:

• Progestogenic & Dopaminergic Effects: Due to its progesterone receptor activity, it can cause or exacerbate prolactin-related side effects, including gynecomastia (even without estrogen conversion) and sexual dysfunction. Management involves the use of dopamine agonists (e.g., Cabergoline, Pramipexole) and monitoring.

• Androgenic Side Effects: Its strong androgenic nature can cause rapid hair loss (in those genetically predisposed), increased sebum production (acne), and heightened aggression or mood changes ("tren rage").

• Cardiovascular Strain: Trenbolone can negatively impact cardiovascular health markers, including raising blood pressure, reducing HDL ("good") cholesterol, and increasing hematocrit (red blood cell count). Regular monitoring, cardio exercise, and cardiovascular support supplements (e.g., fish oil, Hawthorne Berry, CoQ10) are essential.

• Insulin Sensitivity & "Tren Cough": It may reduce glucose tolerance. Post-injection, a rare but acute side effect known as "tren cough" can occur—a sudden, intense coughing fit believed to be caused by the compound acutely affecting pulmonary capillaries.

• Powerful HPTA Suppression: This compound will completely shut down endogenous testosterone production. A structured Post Cycle Therapy (PCT) with SERMs like Clomiphene (Clomid) and Tamoxifen (Nolvadex) is mandatory after the ester has cleared the system, though recovery can be challenging.

Why Choose GENLABS TRENBOLONE ENANTHATE 180mg/mL?

• High Concentration: 180mg/mL allows for lower injection volumes, greater dosing precision, and convenience.

• Pharmaceutical-Grade Raw Materials: GENLABS sources the highest purity trenbolone enanthate raw powder, ensuring product potency and reliability.

• Advanced Sterile Filtration: Manufactured under strict sterile conditions using micron filtration to ensure a clean, safe, and smooth-injecting product.

• Quality Carrier Oils: Formulated with well-tolerated carrier oils to minimize post-injection pain and tissue irritation.

• Third-Party Verification: Every batch is subject to rigorous in-house and independent third-party laboratory testing to verify concentration, sterility, and absence of contaminants.

Disclaimer: This information is for educational and descriptive purposes only. Trenbolone Enanthate is a potent anabolic-androgenic steroid and a controlled substance in most countries. Its use carries significant risk of serious adverse health effects, including cardiovascular disease, liver toxicity, hormonal dysfunction, and psychological changes. This product should only be used under the direct supervision and prescription of a qualified medical professional. The purchase, sale, or use of this product without a prescription may be illegal. Consult with a healthcare professional before considering the use of any anabolic steroid or performance-enhancing drug. GENLABS does not endorse or encourage the illegal or non-medical use of this substance.

Fluoxymesterone, commonly known as Halotestin, is an orally administered synthetic androgenic-anabolic steroid (AAS). It is derived from testosterone and is classified as a C17-alpha-alkylated compound, which means that it has been modified structurally to survive oral ingestion and reach the bloodstream intact.

Halotestin is known for its strong androgenic properties and is primarily used in the medical field to treat conditions such as delayed puberty in males and androgen deficiency in men. However, it is also widely utilized by athletes and bodybuilders for its performance-enhancing effects.

As an androgen, Fluoxymesterone stimulates the development and maintenance of male sexual characteristics. It binds to androgen receptors in various tissues, including skeletal muscle cells, promoting protein synthesis and increasing muscle mass. This is why it is often used by athletes looking to improve their strength and power.

Halotestin is also known for its ability to enhance aggression, competitiveness, and mental focus. Some athletes use it as a pre-workout supplement to boost their energy levels and improve their performance during intense training sessions or competitions. However, it is important to note that the use of Halotestin by athletes for performance enhancement is considered doping and is banned by most sports organizations.

Fluoxymesterone is available in tablet form, with the standard dosage being 10mg. Due to its potent androgenic effects, Halotestin is typically used for short periods of time, usually lasting 4-6 weeks. Prolonged use or high doses can increase the risk of side effects.

Like any AAS, Halotestin comes with potential side effects. These may include liver toxicity, increased cholesterol levels, acne, hair loss, aggression, mood swings, and suppression of natural testosterone production. It is crucial to consult a healthcare professional before using Fluoxymesterone to understand the potential risks and benefits.

In conclusion, Fluoxymesterone (Halotestin) is a synthetic androgenic-anabolic steroid primarily used for medical purposes such as treating delayed puberty and androgen deficiency. However, it is also sought after by athletes and bodybuilders for its muscle-building and performance-enhancing effects. It is essential to use this drug responsibly and under medical supervision to minimize the risk of side effects.

Unlock the Potential of Targeted Growth Hormone Research with CJC 1295 (Without DAC)

In the advanced field of endocrine and metabolic research, the precise modulation of growth hormone (GH) release is a subject of intense study. CJC 1295 (Without DAC), also known as Modified GRF (1-29), represents a pinnacle of peptide engineering designed for investigative purposes. This 2mg vial, provided with bacteriostatic water for reconstitution, offers researchers a highly refined tool to explore the dynamics of GH pulsatility, tissue repair, and metabolic function without the extended activity profile induced by Drug Affinity Complex (DAC) technology.

This product description provides a comprehensive, scientifically-grounded overview of CJC 1295 (Without DAC), detailing its mechanism, key research applications, distinguishing features, and proper handling protocols for the qualified research professional.

Scientific Profile: A Precision Growth Hormone-Releasing Hormone (GHRH) Analog

CJC 1295 is a synthetic analog of the endogenous Growth Hormone-Releasing Hormone (GHRH). The native GHRH, comprising 44 amino acids, is naturally produced by the hypothalamus and stimulates the anterior pituitary gland to secrete growth hormone in a pulsatile manner. The "Without DAC" variant, specifically, is a truncated and modified sequence encompassing the first 29 amino acids of GHRH, with key substitutions to enhance its stability and bioactivity.

Primary Structural Modifications:

1. Substitution of Alanine at position 2: Replacement with D-Alanine significantly reduces degradation by dipeptidyl peptidase-IV (DPP-IV) enzyme, dramatically increasing the peptide's half-life in circulation compared to the native fragment.

2. Other Stabilizing Modifications: Additional amino acid alterations further contribute to metabolic stability and receptor binding affinity.

Crucial Distinction: "Without DAC" vs. "With DAC"
This is the most critical differentiator for researchers. The original CJC 1295 with DAC includes a Drug Affinity Complex that binds the peptide reversibly to albumin in the bloodstream, creating a sustained-release effect with a half-life extending to several days. CJC 1295 Without DAC, as offered in this vial, lacks this complex. Consequently, it has a much shorter half-life (approximately 30 minutes), leading to a sharp, transient, and more physiological pulsatile release of Growth Hormone. This makes it an essential compound for studies aiming to mimic the body's natural GH secretion patterns.

Mechanism of Action: Stimulating the Somatotropic Axis

The action of CJC 1295 (Without DAC) is elegant in its specificity:

1. Receptor Binding: Upon administration, the peptide binds selectively and with high affinity to the GHRH receptors (GHRH-R) located on the somatotroph cells in the anterior pituitary gland.

2. Signal Transduction: This binding activates intracellular cAMP and calcium-dependent signaling pathways.

3. GH Synthesis & Secretion: The signal cascade culminates in the increased synthesis and, most importantly, the rapid secretion of endogenous Growth Hormone into the bloodstream.

4. Downstream IGF-1 Production: The released GH travels to target tissues, primarily the liver, stimulating the production of Insulin-like Growth Factor-1 (IGF-1), a primary mediator of GH's anabolic and metabolic effects.

This entire process amplifies the body's own natural hormonal machinery, making it a subject of interest for research into conditions or states characterized by diminished GH pulsatility.

Key Areas of Research Interest

CJC 1295 (Without DAC) is utilized in preclinical research models to investigate a wide array of physiological processes. Its pulsatile action profile makes it particularly suited for studies on:

• Muscle Tissue Physiology and Recovery: Research focuses on GH's role in promoting protein synthesis, inhibiting protein breakdown, and stimulating satellite cell activation. Studies may explore its potential in models of muscle atrophy, injury repair, and exercise-induced stress.

• Metabolic Function and Body Composition: Investigators examine the peptide's influence on lipid metabolism (increased lipolysis), glucose homeostasis, and energy expenditure. Its role in modulating adipose tissue and supporting lean mass accrual is a significant area of inquiry.

• Connective Tissue and Bone Health: GH and IGF-1 are crucial for collagen synthesis and bone remodeling. Research may target tendon, ligament, and skeletal integrity.

• Sleep and Circadian Endocrinology: Given the natural pulsatile secretion of GH during slow-wave sleep, CJC 1295 (Without DAC) serves as a tool to study the interplay between sleep architecture, GH release, and recovery processes.

• Aging Research: The well-documented decline in GH secretion with age (somatopause) is linked to changes in body composition, vitality, and recovery. Research using this peptide models interventions aimed at restoring a more youthful pulsatile GH profile.

• Comparative Pharmacodynamics: It is often studied in comparison to its DAC-conjugated counterpart and other secretagogues like GHRP-6 or Ipamorelin to contrast pulsatile versus sustained GH release profiles and their distinct physiological outcomes.

Product Features & Quality Assurance

This 2mg vial of CJC 1295 (Without DAC) is manufactured and supplied to meet the exacting standards required for consistent research outcomes.

• High Purity Specification: ≥ 98% purity as verified by High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) analysis.

• Precise Formulation: Each vial contains exactly 2mg of lyophilized (freeze-dried), sterile-filtered peptide powder.

• Sterile Presentation: The peptide is housed in a sterile, tamper-evident glass vial with a rubber stopper and aluminum seal.

• Included Reconstitution Solution: Each peptide vial is paired with a separate 2ml vial of USP-grade Bacteriostatic Water (0.9% Benzyl Alcohol). This sterile solvent is essential for dissolving the peptide and, due to the bacteriostatic agent, allows for multi-dose use when stored correctly post-reconstitution.

• Stability: In its lyophilized state and stored at -20°C or below, the peptide remains stable for extended periods. Once reconstituted with the provided bacteriostatic water, it must be refrigerated and is typically stable for several weeks.

• Intended Use: For laboratory research use only. Not for human or veterinary diagnostic, therapeutic, or consumption purposes. This product is strictly for in-vitro (cell culture) or pre-clinical animal study applications by qualified professionals in controlled laboratory settings.

Recommended Research Protocol & Handling

Reconstitution:

1. Gently inject the bacteriostatic water from the supplied vial into the vial containing the lyophilized CJC 1295 powder.

2. Aim the stream of liquid against the glass wall to minimize forceful impact on the peptide structure.

3. Swirl the vial gently or roll between hands until the powder is fully dissolved. Do not shake vigorously.

Dosage Considerations (Research Models):
Research dosage is highly model-dependent and must be determined by the principal investigator based on study design. Dosages in animal models are typically calculated on a microgram-per-kilogram (μg/kg) basis. The pulsatile nature of the compound often leads to research protocols involving frequent, low-to-moderate dose administrations (e.g., once or twice daily) to simulate endogenous pulses.

Storage:

• Unreconstituted (Lyophilized Powder): Store at or below -20°C in a dedicated freezer. Protect from light.

• Reconstituted Solution: Store refrigerated at 2°C to 8°C in the dark. Use within a timeframe determined by laboratory sterility protocols (typically up to 30 days when reconstituted with bacteriostatic water).

Disclaimer:
This product is sold as a chemical for scientific research. It is the responsibility of the purchasing entity and the principal researcher to comply with all local, state, federal, and institutional guidelines governing the acquisition, handling, and use of bioactive peptides. This description is for informational purposes and does not constitute a medical claim or recommendation.

Tamoxifen is a medication that is widely used in the treatment of breast cancer. It belongs to a class of drugs known as selective estrogen receptor modulators (SERMs). Tamoxifen works by blocking the effects of estrogen in the breast tissue, thus inhibiting the growth of estrogen-dependent cancer cells.

Breast cancer is often hormone receptor positive, meaning it is fueled by estrogen. Tamoxifen helps to counteract this by binding to estrogen receptors on cancer cells and preventing estrogen from binding to these receptors. This action reduces the stimulation of cancer cell growth and division, ultimately leading to the suppression of tumor growth.

Aside from its use in breast cancer treatment, Tamoxifen is also used for the prevention of breast cancer in women at high risk. It has been shown to reduce the incidence of both invasive and non-invasive breast cancer in such cases.

Tamoxifen is usually taken orally in the form of a tablet, typically once or twice daily. The dosage may vary depending on the specific condition being treated and the individual patient. It is important to follow the prescribed dosage and schedule provided by the healthcare provider.

Like any medication, Tamoxifen can have potential side effects. Common side effects may include hot flashes, night sweats, vaginal dryness, irregular menstrual periods, and mood changes. Some women may also experience more serious side effects such as blood clots, stroke, or uterine cancer, although these are relatively rare.

Before starting Tamoxifen, it is crucial to inform your healthcare provider about any pre-existing medical conditions or medications you are currently taking, as they may interact with Tamoxifen. Additionally, women who are pregnant or planning to become pregnant should not take Tamoxifen, as it can harm the developing fetus.

Regular follow-up visits and monitoring are important while taking Tamoxifen. This may include routine breast exams, mammograms, and gynecological evaluations to detect any potential complications or changes in the breast tissue.

In conclusion, Tamoxifen is a widely used medication for the treatment and prevention of breast cancer. It is an effective option for hormone receptor-positive breast cancer and has been beneficial in reducing the risk of developing breast cancer in high-risk individuals. However, it is important to discuss the potential benefits and risks with your healthcare provider before starting Tamoxifen.

Methasterone, also known as Superdrol, is a synthetic androgenic-anabolic steroid that has gained popularity among bodybuilders and athletes seeking to enhance their performance. Developed in the early 2000s, Methasterone quickly became known for its potent anabolic effects, making it a sought-after compound in the world of sports and fitness.

Chemically, Methasterone is derived from dihydrotestosterone (DHT), a naturally occurring hormone in the body. However, Methasterone is modified to enhance its anabolic properties while minimizing its androgenic effects. This modification makes it a highly powerful and efficient compound for muscle growth and strength gains.

Methasterone is available in oral form, typically as a tablet or capsule, making it convenient for users. Its popularity stems from its ability to rapidly increase muscle mass and improve strength, leading to enhanced athletic performance. Bodybuilders often incorporate Methasterone into their bulking cycles to achieve impressive gains in a relatively short period.

When taken, Methasterone interacts with androgen receptors in muscle tissue, stimulating protein synthesis and nitrogen retention. This process leads to an increase in muscle mass, improved recovery, and enhanced endurance. Users often report significant strength gains, allowing them to push their training to the next level.

Methasterone's anabolic effects are remarkable, with some users reporting gains of up to 10 pounds of lean muscle mass in just a few weeks. These gains are often accompanied by an increase in overall body weight due to water retention. However, it's important to note that Methasterone's effects can vary depending on individual genetics, dosage, diet, and training regimen.

Despite its reputation as a powerful muscle-building compound, Methasterone does come with potential side effects. Like other anabolic steroids, it can disrupt the body's natural hormone balance. Common side effects include liver toxicity, acne, hair loss, increased blood pressure, and suppression of natural testosterone production. It is crucial for users to be aware of these risks and take appropriate precautions, such as using liver support supplements and post-cycle therapy (PCT) to restore natural hormone levels.

Due to its androgenic nature, Methasterone may also cause virilization in female users. This means that women who use Methasterone may experience masculinizing effects, such as deepening of the voice, facial hair growth, and clitoral enlargement. As a result, Methasterone is generally not recommended for female athletes or bodybuilders.

In terms of dosage, Methasterone is a potent compound, and users are advised to start with a low dose to assess tolerance. Typical dosages range from 10 to 30 milligrams per day, taken in divided doses. Some experienced users may increase the dosage to 40 milligrams per day, but this should be approached with caution due to the increased risk of side effects.

It is worth noting that Methasterone is classified as a controlled substance in many countries, including the United States. Its use without a prescription is illegal, and athletes who are subject to drug testing may face severe penalties if Methasterone is detected in their system. Therefore, it is essential to understand the legal implications and potential consequences before considering the use of this compound.

In conclusion, Methasterone is a powerful anabolic steroid that has gained popularity among bodybuilders and athletes seeking rapid muscle growth and strength gains. Its ability to stimulate protein synthesis and nitrogen retention makes it an effective tool for enhancing athletic performance. However, users must be aware of the potential side effects and legal implications associated with its use. It is always recommended to consult with a healthcare professional before using any performance-enhancing substances to ensure safety and legality.