MENU
Cart

DSIP 2MG WITH BACTERIOSTATIC WATER – GENLABS

Description for DSIP 2MG WITH BACTERIOSTATIC WATER – GENLABS

Unlocking the Science of Natural Sleep Regulation with DSIP

In the realm of endogenous neuropeptides, Delta Sleep-Inducing Peptide (DSIP) stands out as a uniquely fascinating compound for scientific research. First isolated from the cerebral venous blood of sleeping rabbits, DSIP has since been identified as a natural, sleep-modulating substance within the mammalian brain. GenLabs is proud to offer a premium, laboratory-grade formulation of DSIP 2mg, meticulously paired with a vial of Bacteriostatic Water (0.9% Benzyl Alcohol) to ensure sterility, stability, and precise reconstitution for in-vitro research applications.

This product is designed exclusively for qualified research professionals in controlled laboratory settings. It is not for human or veterinary use. Our DSIP 2mg provides researchers with a highly purified tool to investigate the complex interplay between neuropeptides, sleep architecture, stress physiology, and circadian biology.

Understanding Delta Sleep-Inducing Peptide: A Multifaceted Neuroregulator

DSIP is a nonapeptide (nine amino acids) with a primary sequence of Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. While its name directly references its discovery role in promoting delta-wave (slow-wave) sleep, contemporary research suggests its functions are more nuanced and systemic than initially thought.

  1. Sleep-Wake Cycle Modulation: True to its name, DSIP has been observed to influence the propensity for slow-wave sleep, the deepest and most restorative phase of non-REM sleep. Research indicates it may help normalize sleep patterns without inducing generalized sedation, acting as a homeostatic regulator rather than a classic hypnotic agent.

  2. Stress Response Adaptation: One of the most compelling research avenues for DSIP is its interaction with the hypothalamic-pituitary-adrenal (HPA) axis. Studies suggest DSIP may exhibit modulating effects on cortisol and other stress hormone levels, potentially helping to buffer physiological systems against chronic stress load. This creates a fascinating research link between sleep quality and stress resilience.

  3. Circadian Rhythm Synchronization: Evidence points to DSIP playing a role in entraining biological rhythms. Its secretion appears to follow a diurnal pattern, and administration in research models has been shown to help re-synchronize circadian cycles disrupted by external factors, making it a compound of interest for studying shift-work disorders and jet lag physiology.

  4. Analgesic and Neuroprotective Potential: Preliminary research has explored DSIP's potential role in pain perception pathways and neuronal protection under conditions of oxidative stress, opening further avenues for investigative study.

By providing a pure and reliable source of DSIP, GenLabs empowers researchers to delve deeper into these multifunctional properties within a controlled experimental framework.

GenLabs DSIP: Purity, Precision, and Professional-Grade Quality

At GenLabs, we understand that the integrity of your research begins with the quality of your materials. Our DSIP 2mg is manufactured and verified to the highest standards.

  • Ultra-High Purity (>99%): Each batch is synthesized using advanced solid-phase peptide synthesis (SPPS) and undergoes rigorous purification via HPLC (High-Performance Liquid Chromatography). Certificate of Analysis (CoA) is available upon request, detailing purity, molecular weight confirmation (MW: 848.9 Da), and sterility.

  • Mass Spectrometry (MS) Verified: The amino acid sequence and molecular mass are confirmed by mass spectrometry, ensuring you receive the exact peptide structure required for valid and reproducible results.

  • Lyophilized (Freeze-Dried) Form: The peptide is provided as a sterile, lyophilized white powder in a sealed glass vial to guarantee stability and long-term shelf life when stored correctly.

  • Included Bacteriostatic Water (30ml): We supply a separate vial of sterile bacteriostatic water containing 0.9% benzyl alcohol. This preservative inhibits bacterial growth for multi-use applications post-reconstitution, which is essential for extended in-vitro study protocols.

Reconstitution and Handling Protocol for DSIP 2mg

Important Notice: The following is a general guideline for laboratory reconstitution. Aseptic technique must be used in a sterile environment (e.g., laminar flow hood) to maintain product integrity.

  1. Storage: Store both the lyophilized DSIP and bacteriostatic water vials in a cool, dark place at 2-8°C (36-46°F) prior to reconstitution. Avoid repeated temperature fluctuations.

  2. Preparation: Gently centrifuge the DSIP vial to ensure all powder is at the bottom. Clean the rubber stoppers of both vials with a sterile alcohol swab.

  3. Reconstitution: Using a sterile syringe, slowly draw the desired volume of bacteriostatic water. Gently inject the solvent down the side of the DSIP vial to avoid aggressive agitation. Swirl the vial gently until the powder is fully dissolved. Do not shake vigorously, as this can cause denaturation or foaming.

  4. Concentration Calculation: The final concentration is determined by the amount of bacteriostatic water added.

    • Example: Adding 2ml of bacteriostatic water to the 2mg vial yields a concentration of 1mg/ml (1000mcg/ml).

    • For finer dosing in research, adding 1ml yields 2mg/ml (2000mcg/ml).

  5. Post-Reconstitution Storage: Once reconstituted, the solution should be refrigerated immediately at 2-8°C (36-46°F). The presence of bacteriostatic water typically allows for stable storage for a number of weeks under these conditions. For long-term storage, aliquoting and freezing at -20°C or below is recommended to prevent peptide degradation.

Key Research Areas for Delta Sleep-Inducing Peptide

GenLabs' DSIP 2mg is intended for non-human, in-vitro research in fields such as:

  • Neuroendocrinology: Studying the modulation of the HPA axis and stress hormone feedback loops.

  • Chronobiology: Investigating the peptide's role in circadian pacemaker regulation and rhythm entrainment.

  • Sleep Science: Exploring the endogenous mechanisms of sleep initiation, architecture, and quality.

  • Behavioral Physiology: Researching the links between sleep deprivation, stress, and cognitive performance.

  • Analgesic Research: Preliminary investigation into central and peripheral pain modulation pathways.

Why Choose GenLabs for Your Research Peptides?

Selecting a supplier for sensitive research compounds is a critical decision. GenLabs establishes trust through transparency and quality.

  • Uncompromising Quality Control: Every batch is third-party verified for purity, sterility, and composition.

  • Research-Focused Formulation: Our products are designed and packaged specifically for the rigors of a laboratory environment.

  • Detailed Documentation: Access to comprehensive CoAs and MS sheets ensures full traceability for your research records.

  • Secure & Discreet Shipping: Products are packaged securely and shipped with discretion to research institutions worldwide.

  • Commitment to Compliance: This product is sold for research purposes only in laboratory settings. It is not a drug, nor is it intended for human consumption, diagnosis, or treatment of any condition.

Disclaimer: This information is for educational and research reference purposes only. The products offered are for laboratory research use only. They are not for human or veterinary use, nor for in-vivo diagnosis or treatment. All statements made herein have not been evaluated by any regulatory body. Researchers must operate within the ethical and legal guidelines of their institution and country.

Unlock the potential of neuropeptide research with confidence. Choose GenLabs DSIP 2mg – where precision meets discovery.

Based on 0 review(s)

No review yet

Add a Review

Your Ratings:

Related Products.

HCG (Human Chorionic Gonadotropin) 5000IU is a hormone commonly used in medical and fertility treatments. Here is a detailed description of HCG 5000IU and its uses:

HCG 5000IU: HCG is a glycoprotein hormone that is naturally produced in the placenta during pregnancy. The HCG 5000IU refers to the concentration of the hormone in a single vial or ampoule, which is commonly used in medical and fertility settings.

Medical Uses: HCG has several important medical applications, including:

  1. Fertility Treatment: HCG is commonly used to stimulate ovulation in women who are undergoing fertility treatments, such as in-vitro fertilization (IVF). It helps trigger the release of mature eggs from the ovaries.

  2. Male Hormone Therapy: In men, HCG can be used to stimulate the production of testosterone and maintain normal testosterone levels. It is often prescribed to address hormonal imbalances, such as those related to hypogonadism.

  3. Cryptorchidism: HCG can be used to treat boys with cryptorchidism, a condition where the testicles fail to descend into the scrotum. It helps stimulate testicular descent, allowing for proper development and function.

  4. Weight Loss: HCG is sometimes used as part of a weight loss program. This approach involves a combination of a low-calorie diet and HCG injections, which are believed to help suppress appetite and promote fat loss.

Administration: HCG 5000IU is typically administered by injection, either subcutaneously (under the skin) or intramuscularly (into the muscle). The dosage and duration of treatment will vary depending on the specific medical condition being treated and individual patient factors. It is important to follow the instructions provided by the healthcare professional or fertility specialist.

Side Effects: Like any medication, HCG 5000IU may have potential side effects. Some common side effects include headache, fatigue, breast tenderness or swelling, water retention, and mild abdominal discomfort. These side effects are usually mild and temporary. However, it is important to consult with a healthcare professional if any unusual or severe reactions occur.

Precautions: HCG should be used with caution and under the guidance of a healthcare professional. It is not recommended for use in certain medical conditions, such as hormone-sensitive cancers or early puberty. Inform your healthcare provider about any existing medical conditions or medications you are taking before starting HCG treatment.

Conclusion: HCG 5000IU is a hormone commonly used in medical and fertility treatments. It has various applications, including fertility treatment, male hormone therapy, cryptorchidism, and weight loss. It is administered by injection and should be used under the guidance of a healthcare professional. As with any medication, it is important to be aware of potential side effects and precautions associated with HCG 5000IU. Consult with a healthcare professional for personalized advice and guidance regarding its use.



**Exemestane: A Detailed Description**

Introduction:

Exemestane, also known by its brand name Aromasin, is a medication that belongs to a class of drugs called aromatase inhibitors. It is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. Exemestane works by reducing the production of estrogen in the body, which helps to slow down the growth and spread of cancer cells. In this comprehensive description, we will explore the mechanism of action, therapeutic uses, dosage, side effects, and precautions associated with Exemestane.

Mechanism of Action:

Exemestane works by inhibiting the enzyme aromatase, which is responsible for the conversion of androgens into estrogens. By blocking this enzyme, Exemestane effectively reduces the overall levels of estrogen in the body. Estrogen is a hormone that promotes the growth of hormone receptor-positive breast cancer cells. By decreasing estrogen levels, Exemestane helps to inhibit the growth of cancer cells and prevent their spread to other parts of the body.

Therapeutic Uses:

Exemestane is primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is often prescribed as an adjuvant therapy, meaning it is used in combination with other treatments such as surgery or radiation. Exemestane may be given to patients who have completed several years of tamoxifen therapy or as a first-line treatment for those who cannot tolerate tamoxifen. It is also used in the treatment of advanced breast cancer that has not responded to other hormonal therapies.

Dosage:

The recommended dose of Exemestane for the treatment of breast cancer is 25 mg once daily, preferably after a meal. It is important to take the medication at the same time each day to maintain a consistent level in the body. The duration of treatment may vary depending on the individual's response to therapy and the stage of cancer being treated. It is essential to follow the prescribed dosage and duration as directed by the healthcare professional.

Side Effects:

Like any medication, Exemestane may cause certain side effects. Common side effects include hot flashes, fatigue, headache, joint pain, muscle pain, and increased sweating. These side effects are usually mild and temporary. However, if they become severe or persist for an extended period, it is important to consult a healthcare professional. Additionally, Exemestane may cause more serious side effects such as bone thinning or osteoporosis, high cholesterol levels, and liver problems. Regular monitoring and follow-up with a healthcare provider are necessary to manage and mitigate these risks.

Precautions:

Before starting Exemestane, it is crucial to inform the healthcare provider about any pre-existing medical conditions or allergies. Exemestane is not recommended for use in premenopausal women or individuals with severe liver or kidney problems. It may also interact with certain medications, such as estrogen-containing products or blood thinners, so it is important to disclose all current medications to the healthcare provider. Exemestane should not be used during pregnancy or while breastfeeding, as it may harm the developing fetus or infant.

Conclusion:

Exemestane, also known as Aromasin, is an effective medication used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. By inhibiting the production of estrogen, Exemestane helps slow down the growth and spread of cancer cells. It is an important adjuvant therapy used in combination with other treatments to improve outcomes for breast cancer patients. While Exemestane may cause side effects, most of them are temporary and manageable. It is crucial to follow the prescribed dosage and consult a healthcare professional for any concerns or questions regarding its use. With proper monitoring and care, Exemestane plays a crucial role in the fight against breast cancer.



Introduction: A Cornerstone in Fertility and Endocrine Therapy

For decades, Clomiphene Citrate, most widely recognized under the brand name Clomid, has stood as a foundational and first-line pharmacological intervention in the management of female infertility related to anovulation. However, its therapeutic utility extends far beyond this primary indication, making it a versatile agent in endocrinology. GenLabs presents its professional-grade CLOMID (Clomiphene Citrate) 25mg tablets, supplied in a substantial 200-count package, formulated to the highest standards of purity, consistency, and potency. This detailed description explores the sophisticated mechanism of action, primary and secondary applications, precise dosing protocols, and the critical importance of sourcing from a reputable manufacturer like GenLabs for safety and efficacy.

Understanding the Science: Mechanism of Action

Clomiphene Citrate is classified as a Selective Estrogen Receptor Modulator (SERM). Its profound effects stem from a nuanced interaction with the body's estrogen-sensitive systems. At the hypothalamic-pituitary-ovarian (HPO) axis—the central command center for reproductive hormones—Clomid acts as a competitive estrogen receptor antagonist.

In simple terms, it binds to estrogen receptors in the hypothalamus, blocking the natural estrogen from providing negative feedback. The hypothalamus, perceiving a lower level of circulating estrogen, responds by increasing the secretion of Gonadotropin-Releasing Hormone (GnRH). This, in turn, stimulates the anterior pituitary gland to produce and release elevated levels of Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH).

  • FSH: Promotes the growth and maturation of ovarian follicles.

  • LH: Triggers ovulation (the release of a mature egg from the follicle) and supports the subsequent luteal phase.

This cascade is the cornerstone of its efficacy in treating ovulatory dysfunction. In male and endocrine applications, a similar principle applies at the hypothalamic-pituitary-gonadal (HPG) axis, stimulating the production of endogenous testosterone.

Primary Indication: Treatment of Female Infertility (Anovulation)

GenLabs CLOMID 25mg is meticulously produced to serve as a reliable option for addressing infertility in women who do not ovulate regularly (anovulation), commonly associated with Polycystic Ovary Syndrome (PCOS). The goal is to induce a regular, ovulatory cycle.

  • Typical Clinical Protocol: Treatment usually begins on the 3rd, 4th, or 5th day of the menstrual cycle. A common starting dose is 50mg (two 25mg tablets) daily for five consecutive days. The 25mg tablet strength provides unparalleled dosing flexibility, allowing healthcare providers to tailor treatment precisely—increasing, decreasing, or extending the regimen based on patient response and monitoring (via ultrasound and hormone tests).

  • Success Rates: When used for its primary indication, Clomiphene Citrate successfully induces ovulation in approximately 80% of selected patients, with about 40-50% achieving pregnancy within six treatment cycles. Its use is always recommended under the supervision of a reproductive endocrinologist or gynecologist.

Critical Secondary Applications

The hormonal effects of Clomid make it invaluable in other clinical and therapeutic contexts:

  1. Male Hypogonadism & Infertility: For men with low testosterone (hypogonadism) or certain forms of male infertility (e.g., oligospermia), Clomid acts as an oral stimulant of endogenous testosterone production. By blocking estrogen feedback at the hypothalamus, it increases LH and FSH secretion. LH directly stimulates Leydig cells in the testes to produce testosterone. This offers a potential alternative to exogenous testosterone replacement therapy (TRT), preserving testicular function and fertility.

  2. Post-Cycle Therapy (PCT) in Hormonal Recovery: This is a crucial application in certain therapeutic regimens. After a cycle of exogenous anabolic-androgenic steroids (AAS) or prohormones, the body's natural testosterone production is often suppressed. GenLabs CLOMID is a cornerstone of PCT protocols. It jump-starts the HPG axis, elevating natural LH and FSH levels, thereby accelerating the recovery of endogenous testosterone production, restoring testicular volume, and preventing the loss of gained muscle mass. Its role in mitigating estrogenic side effects post-cycle is also significant.

  3. Estrogen Modulation & Side Effect Management: As a SERM, Clomid can be used to block estrogenic effects in certain tissues. It is sometimes employed to manage or prevent symptoms of estrogen excess, such as gynecomastia, in sensitive individuals during specific therapeutic plans, thanks to its antagonistic action at breast tissue receptors.

Why Choose GenLabs CLOMID 25mg – 200 Tablets?

  1. Pharmaceutical-Grade Quality: GenLabs manufactures its products in facilities adhering to strict quality control standards. Each batch of CLOMID 25mg guarantees >99% purity, ensuring you receive a product free from harmful contaminants and with consistent dosage per tablet.

  2. Optimal Dosage Strength: The 25mg strength is the most versatile formulation available. It allows for fine-tuned, incremental dosing essential for both fertility treatment (where mild stimulation is often key) and sophisticated PCT protocols, minimizing the risk of side effects from unnecessarily high doses.

  3. Exceptional Value & Supply: The 200-tablet package offers a long-term supply, providing cost-effectiveness and continuity for extended treatment plans or multiple therapy cycles without the need for frequent reordering.

  4. Discreet & Secure Packaging: Your order is handled with confidentiality and arrives in secure, tamper-evident, and discreet packaging, protecting your privacy.

Important Considerations, Side Effects, and Contraindications

While highly effective, Clomid is a potent hormonal agent and must be used responsibly.

  • Medical Supervision is Paramount: Consultation with a qualified healthcare professional is non-negotiable before use. Blood work (hormone panels, liver enzymes) and, for women, pelvic monitoring are essential.

  • Potential Side Effects: May include hot flashes, mood swings, visual disturbances (a rare but serious side effect requiring immediate discontinuation), ovarian hyperstimulation (in women), headaches, nausea, and abdominal discomfort. Men may experience emotional volatility.

  • Contraindications: Not for use by pregnant women, individuals with liver disease, abnormal uterine bleeding, ovarian cysts (unrelated to PCOS), or uncontrolled thyroid/adrenal disorders. It may interact with other medications.

Conclusion: A Trusted Tool for Hormonal Health

GenLabs CLOMID (Clomiphene Citrate) 25mg / 200 Tablets represents more than just a product; it is a reliable, high-quality tool for addressing complex endocrine challenges. Whether utilized under medical guidance to realize the dream of conception, to address male hypogonadism, or as part of a responsible post-cycle recovery strategy, its efficacy is rooted in well-established science. The GenLabs commitment to purity, accurate dosing, and volume supply ensures that healthcare professionals and informed users have access to a superior product they can trust.



Sildenafil, commonly known by its brand name Viagra, is a medication primarily used to treat erectile dysfunction (ED) in men. It belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. Sildenafil works by increasing blood flow to the penis, allowing for a firm and lasting erection during sexual stimulation.

Sildenafil was initially developed in the late 1980s as a potential treatment for angina, a condition characterized by chest pain due to inadequate blood flow to the heart. However, during clinical trials, it was observed that sildenafil had a significant effect on penile erections. This accidental discovery led to its approval by the Food and Drug Administration (FDA) in 1998 as the first oral medication for the treatment of ED.

When a man is sexually aroused, the release of nitric oxide in the penis leads to the activation of an enzyme called guanylate cyclase. This enzyme increases the levels of a chemical called cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscles in the blood vessels of the penis. As a result, blood flow to the erectile tissues increases, leading to an erection.

However, another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP and reduces its levels, causing the smooth muscles to contract and impeding blood flow to the penis. Sildenafil inhibits PDE5, allowing cGMP to remain active for longer periods. This sustained increase in cGMP levels helps maintain a firm erection during sexual activity.

Sildenafil is generally taken as needed, approximately 30 minutes to one hour before sexual activity. The medication comes in tablet form, with different strengths available depending on the individual's needs. The recommended starting dose is usually 50 mg, but it can be adjusted based on effectiveness and tolerability.

It's worth noting that sildenafil is not an aphrodisiac and does not increase sexual desire. It only facilitates the physiological process of achieving an erection when sexual stimulation is present. It is important to consult with a healthcare professional before starting sildenafil treatment, as they can determine the appropriate dosage and assess any potential contraindications or interactions with other medications.

While sildenafil is generally well-tolerated, it may cause some side effects. Common side effects include headache, flushing, indigestion, nasal congestion, and dizziness. In rare cases, more serious side effects such as priapism (prolonged erection lasting more than four hours) or sudden vision or hearing loss may occur. If any severe or persistent side effects are experienced, medical attention should be sought immediately.

Additionally, it is important to note that sildenafil should not be taken by individuals who are using organic nitrates or nitric oxide donors, as combining these medications can cause a dangerous drop in blood pressure. It is also contraindicated in individuals with certain cardiovascular conditions, liver or kidney disease, or those taking specific medications that could interact with sildenafil.

In summary, sildenafil (Viagra) is an oral medication used to treat erectile dysfunction by increasing blood flow to the penis. It is a reliable and widely-used treatment option that has helped millions of men regain their sexual confidence. However, it is essential to consult with a healthcare professional to ensure its safe and effective use.



GENLABS FOXO4-DRI 10mg (with Bacteriostatic Water) | A High-Purity Research Peptide for Cellular Senescence Studies

Product Name: GENLABS FOXO4-DRI 10mg Research Peptide Kit (Including 1x 10mg FOXO4-DRI Lyophilized Powder & 1x 10ml Bacteriostatic Water)
CAS Number: [To be filled by GENLABS - e.g., 2212441-64-0]
Molecular Formula: C₁₈₇H₃₁₀N₅₆O₅₃S
Sequence: D-Y-R-K-L-L-Q-K-R-K-R-Q-Q-R-R-P-P-S-C*
Purity: ≥98% (as verified by HPLC-MS)
Storage: Store lyophilized powder at -20°C or below. Reconstituted solution should be stored at 2-8°C and used within a specified research timeframe.

Introduction: Targeting the Pivotal Senescence Pathway

In the advancing field of biogerontology and cellular biology, the study of cellular senescence represents a cornerstone for understanding age-related physiological decline. Senescent cells, characterized by their irreversible cell cycle arrest and the secretion of pro-inflammatory factors (the Senescence-Associated Secretory Phenotype, SASP), accumulate with age and contribute significantly to tissue dysfunction. GENLABS introduces FOXO4-DRI 10mg, a highly specific, research-grade peptide designed to disrupt a key protein-protein interaction involved in senescence maintenance. This product, provided as a complete kit with bacteriostatic water, offers scientists a precise and reliable tool for in vitro and pre-clinical investigation into senolytic strategies—the selective clearance of senescent cells.

Mechanism of Action: A Disruptor of the FOXO4-p53 Interaction

FOXO4-DRI (FOXO4-D-Retro-Inverso) is a rationally designed, cell-permeable peptide with a novel retro-inverso structure. This design confers enhanced stability and bioavailability in biological systems compared to its linear counterpart. Its primary target is the forkhead box O4 (FOXO4) transcription factor and its interaction with the tumor suppressor protein p53.

In senescent cells, p53 is typically sequestered in the nucleus by FOXO4. This interaction is a critical mechanism that prevents p53 from initiating apoptosis (programmed cell death) in the senescent cell. FOXO4-DRI functions as a competitive inhibitor:

  1. Specific Binding: The peptide's structure mimics the domain on FOXO4 that binds to p53.

  2. Displacement: By binding with high affinity to p53, FOXO4-DRI displaces FOXO4, breaking the inhibitory complex.

  3. p53 Activation & Apoptosis: Once freed from FOXO4, p53 can migrate to the mitochondria and initiate the intrinsic apoptotic pathway, leading to the selective elimination of the senescent cell.

  4. Selectivity: This mechanism is preferentially active in cells where the FOXO4-p53 interaction is a dominant survival signal—primarily senescent cells—potentially offering a targeted senolytic effect while sparing healthy, proliferating cells in research models.

Key Research Applications & Potential Investigative Pathways

GENLABS FOXO4-DRI is intended for laboratory research use only. It serves as a critical reagent in the following potential areas of study:

  • Senolysis and Age-Related Research: Investigating the direct clearance of senescent cells from various tissues (e.g., dermal fibroblasts, endothelial cells, hepatocytes) in model systems and observing subsequent tissue function.

  • SASP Modulation Studies: Assessing the downstream effects of senescent cell removal on the inflammatory microenvironment by measuring changes in SASP factors like IL-6, IL-1α, MMPs, and others.

  • Healthspan and Function Studies: Exploring correlations between senolytic interventions and improvements in physiological function, resilience to stress, and tissue regeneration capacity in research models.

  • Model System Development: Utilizing FOXO4-DRI as a positive control or benchmark compound when validating new senolytic agents or cellular senescence assays.

  • Mechanistic Biology: Further elucidating the intricate signaling networks between FOXO proteins, p53 dynamics, and cell fate decisions in the context of stress and aging.

Why Choose GENLABS FOXO4-DRI?

  1. Exceptional ≥98% Purity: Every batch is rigorously analyzed via High-Performance Liquid Chromatography and Mass Spectrometry (HPLC-MS), ensuring minimal impurities and maximum consistency for your experimental results.

  2. Complete Research Kit: Each order contains one 10mg vial of lyophilized FOXO4-DRI peptide and one 10ml vial of sterile, pH-balanced Bacteriostatic Water (0.9% Benzyl Alcohol). This provides everything needed for sterile reconstitution, eliminating sourcing variables.

  3. Stable Retro-Inverso Design: The D-amino acid, reverse-sequence structure offers superior resistance to proteolytic degradation compared to L-peptides, leading to longer activity and more reliable data in cellular and pre-clinical research settings.

  4. Sterile, Lyophilized Format: The peptide is sterile-filtered and lyophilized in a cleanroom environment to ensure stability, longevity, and readiness for precise reconstitution.

  5. Commitment to Research Integrity: GENLABS provides comprehensive supporting documentation, including Certificate of Analysis (CoA) with lot-specific purity data and MS/HRMS verification. Our products are designed solely for use in controlled laboratory settings by qualified researchers.

Reconstitution, Handling & Important Research Notes

Reconstitution Protocol:

  1. Gently swirl the bacteriostatic water vial.

  2. Aseptically, draw the desired volume of bacteriostatic water.

  3. Slowly inject the water down the side of the FOXO4-DRI vial to avoid aggressive foaming.

  4. Gently swirl or roll the vial until the lyophilized cake is fully dissolved. Do not vortex aggressively.

  5. The reconstituted peptide solution should be clear and colorless.

Typical Research Dosage & Storage:

  • In Vitro Concentrations: Research often utilizes concentrations ranging from 1-10 µM, though optimal dosing must be empirically determined for each specific cell type and assay.

  • Post-Reconstitution Storage: The reconstituted solution is stable for approximately 30 days when stored refrigerated at 2-8°C. For long-term stability, aliquoting and storage at -20°C or -80°C is recommended. Avoid repeated freeze-thaw cycles.

  • Lyophilized Powder: Store unopened vials at -20°C or below for long-term stability (up to 24 months).

Disclaimer & Safety Information

INTENDED USE STATEMENT: GENLABS FOXO4-DRI 10mg is sold strictly as a research chemical for laboratory and scientific investigation purposes only. It is not for human or veterinary use, not for ingestion, injection, or any form of personal consumption. It is not a drug, dietary supplement, or cosmetic ingredient. This product has not been evaluated or approved by the FDA or any other regulatory body for the diagnosis, treatment, cure, or prevention of any disease or condition.

Safety: Researchers must handle all peptides using appropriate laboratory safety protocols, including the use of personal protective equipment (PPE) such as gloves, lab coats, and eye protection. Assume all materials require sterile technique for cell culture applications.

Order Your Research Kit Today

Elevate your cellular senescence and longevity research with the precision and quality of GENLABS. Our FOXO4-DRI 10mg kit provides a reliable, high-purity tool to probe the frontiers of senolytic biology. Visit the GENLABS website to view the Certificate of Analysis for this product, explore our full portfolio of research peptides, and place your order.



Nandrolone Decanoate, commonly known by its brand name Deca-Durabolin, is a synthetic anabolic androgenic steroid (AAS) that is widely used in the field of sports and bodybuilding. It is a slow-acting ester of nandrolone, which is a modified form of testosterone. Nandrolone Decanoate is highly regarded for its strong anabolic properties and relatively mild androgenic effects.

The standard dosage of Nandrolone Decanoate is typically 300mg per week, although dosages can vary depending on individual goals and experience. It is commonly administered through intramuscular injection, usually in the gluteal region. This dosage is often divided into two injections per week to maintain stable blood levels and reduce the risk of side effects.

One of the key benefits of Nandrolone Decanoate is its ability to promote protein synthesis and nitrogen retention in the muscles. This results in increased muscle mass, strength, and endurance. It also helps in the repair and recovery of damaged tissues, making it popular among athletes and bodybuilders during bulking and cutting phases.

Nandrolone Decanoate has a long half-life, meaning it remains active in the body for an extended period. This allows for less frequent injections compared to other steroids. However, it also means that it may take a while for the full effects to be noticed, and it can stay detectable in the body for several months after use.

While Nandrolone Decanoate offers numerous benefits, it is important to note that it is not without potential side effects. Some common side effects include water retention, increased blood pressure, acne, and oily skin. It is also known to have a suppressive effect on natural testosterone production, which can lead to hormonal imbalances and testicular atrophy. To mitigate these effects, a post-cycle therapy (PCT) is often recommended to help restore natural hormone levels.

It is crucial to emphasize that the use of Nandrolone Decanoate should only be undertaken under the guidance of a qualified medical professional or experienced fitness expert. It is classified as a controlled substance in many countries, and its misuse or abuse can lead to serious health risks.

Overall, Nandrolone Decanoate (Deca-Durabolin) is a potent steroid that offers significant benefits for muscle growth and performance enhancement. However, its use should be approached with caution, and individuals should be aware of the potential risks and side effects associated with its usage.



Unlock Confident, Spontaneous, and Long-Lasting Performance with GenLabs Cialis (Tadalafil)

For men experiencing erectile dysfunction (ED), the quest for a reliable, effective, and lasting solution can be a source of significant stress and diminished quality of life. Introducing GenLabs Cialis (Tadalafil) 20mg—a premium-quality, generic pharmaceutical engineered to provide up to 36 hours of continuous efficacy, transforming the approach to treating ED. This 30-tablet pack offers a convenient and cost-effective solution, delivering the same proven active ingredient, Tadalafil, as the brand-name medication, but with the trusted value of GenLabs.

Understanding Erectile Dysfunction and How Cialis (Tadalafil) Works

Erectile Dysfunction is a common medical condition characterized by the consistent inability to achieve or maintain a firm erection sufficient for satisfactory sexual activity. It is often linked to underlying physical factors such as reduced blood flow due to cardiovascular conditions, diabetes, or hypertension, as well as psychological factors like stress and anxiety.

GenLabs Cialis 20mg works at the physiological root of the problem. The active ingredient, Tadalafil, belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. During sexual stimulation, the body naturally releases nitric oxide, which triggers the production of cyclic guanosine monophosphate (cGMP). This chemical relaxes the smooth muscles in the penile arteries, allowing for increased blood flow and a natural erection. In men with ED, an enzyme called PDE5 breaks down cGMP too quickly. Tadalafil inhibits the PDE5 enzyme, allowing cGMP levels to remain elevated, thereby facilitating and sustaining a robust erection in response to sexual stimulation.

The Unmatched "36-Hour" Advantage: Redefine Your Spontaneity

While other ED medications offer a 4-6 hour window of opportunity, GenLabs Cialis 20mg is renowned for its groundbreaking 36-hour duration of action. This is not a 36-hour constant erection; rather, it is a prolonged therapeutic window during which you can respond naturally to sexual stimulation. This unique benefit has earned it the nickname "The Weekend Pill."

This extended efficacy means:

  • Freedom from Timing Anxiety: Move away from the pressure of a short, strict window. The 36-hour coverage allows for a more relaxed, natural, and spontaneous intimate life.

  • Enhanced Confidence: Knowing you are prepared for an extended period reduces performance anxiety, allowing you to focus on the moment.

  • Flexibility for Multiple Opportunities: Suitable for couples who prefer intimacy at different times over a day or throughout a weekend getaway.

Dosage, Administration, and Recommended Use

This product is GenLabs Cialis (Tadalafil) 20mg tablets, supplied in a convenient pack of 30. The 20mg strength is the maximum recommended single dose for on-demand treatment of ED.

  • Standard On-Demand Dose: Take one 20mg tablet at least 30 minutes before anticipated sexual activity. It can be taken with or without food, though consuming it with a high-fat meal may slightly delay the onset of effect.

  • Do Not Exceed One Dose in a 24-Hour Period.

  • Once-Daily Low-Dose Option: It is important to note that Tadalafil is also prescribed in lower doses (2.5mg or 5mg) for daily use. The 20mg tablet is not intended for daily use unless specifically instructed by a physician for that regimen. Always follow your doctor's prescription.

  • Optimal Results: The medication requires sexual arousal to work. It will not cause an automatic erection.

Why Choose GenLabs Cialis 20mg?

1. Pharmaceutical Grade Quality & Bioequivalence: GenLabs manufactures this Tadalafil to stringent international Good Manufacturing Practice (GMP) standards. It is bioequivalent to the brand-name Cialis, meaning it delivers the same amount of active ingredient into your bloodstream at the same rate, ensuring identical efficacy and safety.

2. Exceptional Value: By opting for the generic GenLabs version, you access the profound benefits of Tadalafil without the premium brand-name price. The 30-tablet pack offers extended supply and greater savings per dose.

3. Discreet and Convenient Packaging: The product is delivered in secure, discreet packaging, respecting your privacy. The 30-count supply reduces the frequency of reordering.

Important Safety Information, Side Effects, and Contraindications

Consult a healthcare professional before use to ensure this medication is appropriate for you.

  • Contraindications: Do not take GenLabs Cialis 20mg if you:

    • Use any form of organic nitrates (e.g., nitroglycerin for chest pain) or guanylate cyclase stimulators (e.g., riociguat). The combination can cause a dangerous, sudden drop in blood pressure.

    • Have severe cardiovascular disease (e.g., unstable angina, severe heart failure), recent stroke, or myocardial infarction.

    • Have severe liver or kidney impairment. Dose adjustment may be required.

    • Have a known hypersensitivity to Tadalafil.

  • Common Side Effects: May include headache, flushing, indigestion, back pain, muscle aches, nasal congestion, and dizziness. These are typically mild to moderate and transient.

  • Serious Side Effects (Seek medical help if experienced): Priapism (a painful erection lasting more than 4 hours), sudden vision loss (NAION), sudden hearing loss, or symptoms of a cardiovascular event (chest pain, dizziness, nausea). Allergic reactions are rare but possible.

  • Drug Interactions: Inform your doctor about all medications you take, especially alpha-blockers (for prostate issues), other ED medications, antihypertensives, and strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir).

Invest in Your Confidence and Relationship Health

Erectile dysfunction is a treatable medical condition. GenLabs Cialis (Tadalafil) 20mg provides a powerful, long-lasting, and clinically proven solution to restore your sexual function and, more importantly, your confidence and intimate connections. The 36-hour window liberates you from the constraints of timing, fostering a more authentic and spontaneous relationship dynamic.

Disclaimer: This information is for educational purposes and does not constitute medical advice. Always consult with a licensed physician for a proper diagnosis and treatment plan tailored to your individual health profile and needs. Do not start or stop any medication without professional consultation.



Achieve the Coveted Pearl Glow: Introducing Golden Pearl Beauty Face Cream

For centuries, the luminous, flawless beauty of pearls has been the ultimate symbol of purity and radiant elegance. Yet, achieving such clarity and glow in our complexion often feels like a distant dream, obscured by the challenges of hyperpigmentation, dullness, and uneven skin tone. Golden Pearl Cosmetics bridges this timeless inspiration with modern skincare science to present the Golden Pearl Beauty Face Cream. This is not merely a moisturizer; it is a dedicated treatment cream meticulously crafted to transform your skin into a canvas of clarity, spot-free smoothness, and a natural, lit-from-within luminosity.

Our advanced, dermatologically-informed formula is a symphony of potent brightening agents, deep hydrators, and protective antioxidants. It works synergistically to target dark spots, fade post-acne marks, prevent new blemishes, and nourish your skin to reveal a healthier, more even, and noticeably radiant version of itself. If you seek a complexion that reflects the inner glow of a pearl—smooth, clear, and incandescent—your journey begins here.

The Core Promise: Clear, Spot-Free, and Glowing Skin

The Golden Pearl Beauty Face Cream is built upon a triple-action promise that addresses the most common skin concerns holistically:

  1. CLEAR & SPOT-FREE: The formula actively works to inhibit melanin overproduction, the primary cause of dark spots, sun spots, and post-inflammatory hyperpigmentation (PIH). It helps break down existing pigmentation clusters, gradually fading discoloration for a remarkably uniform skin tone.

  2. RADIANT GLOW: Dull, tired skin is revitalized. The cream sloughs away dead surface cells that obscure your natural radiance, promotes smoother skin texture, and enhances light reflection. The result is a vibrant, healthy glow that looks and feels authentic.

  3. DEEPLY NOURISHED & BALANCED: Beyond brightening, it provides intense, non-comedogenic hydration. This strengthens the skin's moisture barrier, preventing dryness-induced irritation and excess oil production—a key factor in maintaining clear, balanced, and resilient skin.

Decoding the Science of Luminosity: Key Ingredients & Their Benefits

The efficacy of the Golden Pearl Beauty Face Cream stems from a carefully curated blend of high-performance and nurturing ingredients.

  • Pearl Extract (The Signature Elixir): The heart of our formulation. Rich in amino acids, minerals, and conchiolin, Pearl Extract is revered for its skin-brightening and revitalizing properties. It helps to even out skin tone, improve elasticity, and impart a soft, pearlescent sheen to the skin's surface.

  • Potent Vitamin E (Tocopherol): A superstar antioxidant that defends skin against daily environmental aggressors like pollution and UV free radicals. It supports skin repair, soothes dryness, and works in tandem with brightening agents to enhance their efficacy and promote a healthier complexion.

  • Licorice Root Extract: A natural, skin-friendly brightening agent. Its active component, Glabridin, helps to reduce melanin synthesis, effectively targeting dark spots and redness while providing calming, anti-inflammatory benefits—ideal for sensitive or post-blemish skin.

  • Niacinamide (Vitamin B3): A multi-tasking marvel. Niacinamide minimizes the appearance of pores, improves skin texture, reduces sebum production, and fortifies the skin barrier. Crucially, it is clinically proven to reduce the transfer of pigment to skin cells, making it essential for fading discoloration and preventing new spots.

  • Advanced Hydration Complex: A blend of Hyaluronic Acid and Glycerin draws moisture deep into the epidermis, ensuring plump, dewy, and supremely supple skin without heaviness or greasiness.

Who is the Golden Pearl Beauty Face Cream For?

This cream is the ideal solution for individuals who:

  • Struggle with uneven skin tone, dark spots, or post-acne marks.

  • Desire a brighter, more radiant complexion but find their skin looks dull or fatigued.

  • Seek a daily moisturizer that offers both treatment benefits and luxurious hydration.

  • Have combination to normal skin types (a patch test is recommended for very sensitive skin).

  • Believe in a skincare ritual that feels both efficacious and indulgent.

The Golden Pearl Ritual: How to Use for Optimal Results

Incorporate this cream into your daily routine for transformative, cumulative results.

Morning:

  1. Cleanse your face with a gentle, pH-balanced cleanser.

  2. Apply toner and serum (preferably a Vitamin C serum for enhanced brightening).

  3. Take a pearl-sized amount of Golden Pearl Beauty Face Cream and gently massage it onto your face and neck using upward, circular motions.

  4. Always follow with a broad-spectrum sunscreen of SPF 30 or higher. This is non-negotiable to protect your skin and prevent new dark spots from forming.

Evening:

  1. Thoroughly remove makeup and cleanse.

  2. Apply your preferred treatment serums (such as retinol or exfoliating acids on alternate nights, if used).

  3. As the final step, apply a slightly thicker layer of Golden Pearl Beauty Face Cream to allow the active ingredients to work in harmony with your skin's natural overnight renewal process.

A Commitment to Conscious Luxury

At Golden Pearl Cosmetics, beauty is synonymous with integrity. The Beauty Face Cream is:

  • Dermatologically Tested: Formulated under guidance to ensure safety and efficacy.

  • Non-Comedogenic: Designed not to clog pores.

  • Paraben-Free & Sulfate-Free: We prioritize skin-friendly formulations.

  • Cruelty-Free: We never test on animals.

  • Elegantly Packaged: Housed in a protective jar that preserves the potency of the active ingredients and adds a touch of luxury to your vanity.

FAQs: Your Questions, Answered

Q: How soon will I see results?
A: While some users report a noticeable improvement in hydration and glow within the first week, significant brightening and spot-fading are progressive. Consistent use for 4-6 weeks is typically needed to see visible changes in hyperpigmentation and overall clarity.

Q: Can I use this cream if I have sensitive skin?
A: Our formula is created to be gentle yet effective. However, if you have highly reactive skin, we recommend performing a patch test on the inner arm 24 hours before full facial application.

Q: Is this cream suitable for daytime use under makeup?
A: Absolutely. Its fast-absorbing, non-greasy texture makes it a perfect hydrating primer, creating a smooth canvas for seamless makeup application.

Q: Does this cream contain steroids or hydroquinone?
A: No. The Golden Pearl Beauty Face Cream relies on a blend of natural extracts, vitamins, and scientifically-backed brightening agents like Niacinamide and Licorice Root. It is free from harsh steroids and hydroquinone.

Embrace Your Transformation

Your journey to a flawless, radiant complexion is a testament to self-care. The Golden Pearl Beauty Face Cream is more than a skincare product; it is a daily affirmation of your commitment to unveiling your most beautiful skin. It represents the fusion of nature’s timeless wisdom with meticulous scientific innovation—all designed to give you the confidence that comes from a clear, spot-free, and luminously glowing face.

Stop dreaming of pearlescent skin. Start living it.



#

Shipping Cost

On all orders is set at $25.00

#

Secure checkout

Protected by Bitcoin

#

Offer & gift here

On all huge orders