In the realm of endogenous neuropeptides, Delta Sleep-Inducing Peptide (DSIP) stands out as a uniquely fascinating compound for scientific research. First isolated from the cerebral venous blood of sleeping rabbits, DSIP has since been identified as a natural, sleep-modulating substance within the mammalian brain. GenLabs is proud to offer a premium, laboratory-grade formulation of DSIP 2mg, meticulously paired with a vial of Bacteriostatic Water (0.9% Benzyl Alcohol) to ensure sterility, stability, and precise reconstitution for in-vitro research applications.
This product is designed exclusively for qualified research professionals in controlled laboratory settings. It is not for human or veterinary use. Our DSIP 2mg provides researchers with a highly purified tool to investigate the complex interplay between neuropeptides, sleep architecture, stress physiology, and circadian biology.
DSIP is a nonapeptide (nine amino acids) with a primary sequence of Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu. While its name directly references its discovery role in promoting delta-wave (slow-wave) sleep, contemporary research suggests its functions are more nuanced and systemic than initially thought.
Sleep-Wake Cycle Modulation: True to its name, DSIP has been observed to influence the propensity for slow-wave sleep, the deepest and most restorative phase of non-REM sleep. Research indicates it may help normalize sleep patterns without inducing generalized sedation, acting as a homeostatic regulator rather than a classic hypnotic agent.
Stress Response Adaptation: One of the most compelling research avenues for DSIP is its interaction with the hypothalamic-pituitary-adrenal (HPA) axis. Studies suggest DSIP may exhibit modulating effects on cortisol and other stress hormone levels, potentially helping to buffer physiological systems against chronic stress load. This creates a fascinating research link between sleep quality and stress resilience.
Circadian Rhythm Synchronization: Evidence points to DSIP playing a role in entraining biological rhythms. Its secretion appears to follow a diurnal pattern, and administration in research models has been shown to help re-synchronize circadian cycles disrupted by external factors, making it a compound of interest for studying shift-work disorders and jet lag physiology.
Analgesic and Neuroprotective Potential: Preliminary research has explored DSIP's potential role in pain perception pathways and neuronal protection under conditions of oxidative stress, opening further avenues for investigative study.
By providing a pure and reliable source of DSIP, GenLabs empowers researchers to delve deeper into these multifunctional properties within a controlled experimental framework.
At GenLabs, we understand that the integrity of your research begins with the quality of your materials. Our DSIP 2mg is manufactured and verified to the highest standards.
Ultra-High Purity (>99%): Each batch is synthesized using advanced solid-phase peptide synthesis (SPPS) and undergoes rigorous purification via HPLC (High-Performance Liquid Chromatography). Certificate of Analysis (CoA) is available upon request, detailing purity, molecular weight confirmation (MW: 848.9 Da), and sterility.
Mass Spectrometry (MS) Verified: The amino acid sequence and molecular mass are confirmed by mass spectrometry, ensuring you receive the exact peptide structure required for valid and reproducible results.
Lyophilized (Freeze-Dried) Form: The peptide is provided as a sterile, lyophilized white powder in a sealed glass vial to guarantee stability and long-term shelf life when stored correctly.
Included Bacteriostatic Water (30ml): We supply a separate vial of sterile bacteriostatic water containing 0.9% benzyl alcohol. This preservative inhibits bacterial growth for multi-use applications post-reconstitution, which is essential for extended in-vitro study protocols.
Important Notice: The following is a general guideline for laboratory reconstitution. Aseptic technique must be used in a sterile environment (e.g., laminar flow hood) to maintain product integrity.
Storage: Store both the lyophilized DSIP and bacteriostatic water vials in a cool, dark place at 2-8°C (36-46°F) prior to reconstitution. Avoid repeated temperature fluctuations.
Preparation: Gently centrifuge the DSIP vial to ensure all powder is at the bottom. Clean the rubber stoppers of both vials with a sterile alcohol swab.
Reconstitution: Using a sterile syringe, slowly draw the desired volume of bacteriostatic water. Gently inject the solvent down the side of the DSIP vial to avoid aggressive agitation. Swirl the vial gently until the powder is fully dissolved. Do not shake vigorously, as this can cause denaturation or foaming.
Concentration Calculation: The final concentration is determined by the amount of bacteriostatic water added.
Example: Adding 2ml of bacteriostatic water to the 2mg vial yields a concentration of 1mg/ml (1000mcg/ml).
For finer dosing in research, adding 1ml yields 2mg/ml (2000mcg/ml).
Post-Reconstitution Storage: Once reconstituted, the solution should be refrigerated immediately at 2-8°C (36-46°F). The presence of bacteriostatic water typically allows for stable storage for a number of weeks under these conditions. For long-term storage, aliquoting and freezing at -20°C or below is recommended to prevent peptide degradation.
GenLabs' DSIP 2mg is intended for non-human, in-vitro research in fields such as:
Neuroendocrinology: Studying the modulation of the HPA axis and stress hormone feedback loops.
Chronobiology: Investigating the peptide's role in circadian pacemaker regulation and rhythm entrainment.
Sleep Science: Exploring the endogenous mechanisms of sleep initiation, architecture, and quality.
Behavioral Physiology: Researching the links between sleep deprivation, stress, and cognitive performance.
Analgesic Research: Preliminary investigation into central and peripheral pain modulation pathways.
Selecting a supplier for sensitive research compounds is a critical decision. GenLabs establishes trust through transparency and quality.
Uncompromising Quality Control: Every batch is third-party verified for purity, sterility, and composition.
Research-Focused Formulation: Our products are designed and packaged specifically for the rigors of a laboratory environment.
Detailed Documentation: Access to comprehensive CoAs and MS sheets ensures full traceability for your research records.
Secure & Discreet Shipping: Products are packaged securely and shipped with discretion to research institutions worldwide.
Commitment to Compliance: This product is sold for research purposes only in laboratory settings. It is not a drug, nor is it intended for human consumption, diagnosis, or treatment of any condition.
Disclaimer: This information is for educational and research reference purposes only. The products offered are for laboratory research use only. They are not for human or veterinary use, nor for in-vivo diagnosis or treatment. All statements made herein have not been evaluated by any regulatory body. Researchers must operate within the ethical and legal guidelines of their institution and country.
Unlock the potential of neuropeptide research with confidence. Choose GenLabs DSIP 2mg – where precision meets discovery.
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