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BETNOVATE – NBETAMETHASONE VALERATE AND NEOMY

Description for BETNOVATE – NBETAMETHASONE VALERATE AND NEOMY

Comprehensive Product Overview: BETNOVATE-N Cream (Betamethasone Valerate & Neomycin Sulfate) 25g by GlaxoSmithKline

In the realm of dermatological therapeutics, the management of inflammatory skin conditions complicated by bacterial infection demands a dual-action approach. BETNOVATE-N Cream, manufactured by the globally renowned pharmaceutical leader GlaxoSmithKline (GSK), stands as a meticulously formulated solution designed to address this very challenge. This prescription medication combines the anti-inflammatory potency of a corticosteroid with the protective coverage of a trusted antibiotic, offering patients a comprehensive treatment modality in a convenient 25-gram tube.

Understanding the Dual-Active Formula: Synergy for Skin Health

The efficacy of BETNOVATE-N Cream lies in its two-pronged pharmacological action, delivered through its key active ingredients:

  1. Betamethasone Valerate (0.1% w/w): This is a potent topical corticosteroid, a gold-standard class of medication for reducing inflammation. It works by mimicking the effects of natural hormones produced by the adrenal glands. Upon application, it penetrates the skin to exert powerful anti-inflammatory, anti-pruritic (anti-itch), and vasoconstrictive actions. It effectively suppresses the immune system's localized overreaction that causes redness, swelling, heat, and itching associated with various dermatoses. By stabilizing cell membranes and inhibiting the release of pro-inflammatory substances, it provides rapid symptomatic relief and helps restore skin calm.

  2. Neomycin Sulfate (0.5% w/w): This is a broad-spectrum aminoglycoside antibiotic. Its inclusion is critical for combating secondary bacterial infections that often exploit inflamed, broken, or weeping skin. Neomycin is effective against a range of common gram-positive and gram-negative bacteria, including Staphylococcus aureus, a frequent culprit in infected eczema. By eliminating or preventing bacterial colonization, it allows the skin's natural barrier to heal without the added complication of infection, which can worsen inflammation and delay recovery.

The synergy between these components makes BETNOVATE-N not merely a cream for inflammation or for infection alone, but a targeted treatment for inflamed skin conditions where bacterial infection is present or likely to occur.

Indications: When is BETNOVATE-N Cream Prescribed?

Healthcare professionals typically prescribe BETNOVATE-N Cream for short-term treatment of acute flare-ups of specific steroid-responsive dermatoses where bacterial infection is a factor. Key indications include:

  • Infected Eczema (Atopic Dermatitis): When eczema patches become weepy, crusted, or show signs of infection.

  • Psoriasis (particularly in stages prone to cracking or infection): For plaques that are inflamed and potentially infected.

  • Contact Dermatitis: Allergic or irritant reactions that have become secondarily infected due to scratching.

  • Seborrhoeic Dermatitis: Especially in severe or infected cases.

  • Lichen Simplex Chronicus: Thickened, leathery skin patches caused by repeated scratching that may develop infection.

  • Other Inflammatory Conditions: As determined by a dermatologist or physician, where both inflammation and bacterial control are needed.

Key Benefits and Advantages of Choosing BETNOVATE-N by GSK

  • Dual-Action Efficacy: Addresses both the root inflammatory response and the complicating bacterial infection simultaneously, streamlining treatment.

  • Rapid Symptom Relief: The potent corticosteroid action quickly reduces itching, redness, swelling, and discomfort, improving quality of life.

  • Infection Control & Prevention: Neomycin sulfate helps clear existing mild infections and protects vulnerable skin from further bacterial invasion during the healing process.

  • Trusted Pharmaceutical Heritage: Manufactured by GlaxoSmithKline, a company with a long-standing global reputation for quality, research, and rigorous manufacturing standards.

  • Patient-Friendly Format: The 25g tube is convenient for targeted application, portable, and suitable for course-based treatment as directed by a physician.

Guidelines for Application: How to Use BETNOVATE-N Cream Correctly

Crucial Reminder: This is a prescription medicine. Use exactly as directed by your doctor. The following are general guidelines.

  1. Preparation: Wash your hands thoroughly. Gently clean and dry the affected skin area. Ensure it is free from other products.

  2. Application: Apply a thin smear of cream to completely cover the affected area. As a general rule, one fingertip unit (the amount squeezed from the tube to cover the distal phalanx of an adult index finger) is enough to treat an area twice the size of an adult hand.

  3. Massage: Gently rub the cream into the skin until it disappears. It is designed for topical use only.

  4. Frequency: Typically applied 1-2 times daily, as prescribed. Do not use more frequently or over larger areas than advised.

  5. Duration: Use for the shortest period necessary to control symptoms. Long-term continuous use should be avoided unless under strict medical supervision.

  6. Hygiene: Wash your hands after application, unless treating the hands themselves.

Important Safety Information, Warnings, and Side Effects

While effective, BETNOVATE-N Cream requires informed use due to the potency of its ingredients.

  • Prescription Only: Never use this medication without a doctor's diagnosis and prescription.

  • Not for All Infections: Neomycin is not effective against fungal infections (like ringworm, athlete's foot) or viral infections (like herpes, warts). Misdiagnosis can worsen these conditions.

  • Avoid on the Face: Unless specifically instructed by a doctor, do not use on the face, as facial skin is more prone to corticosteroid side effects like thinning, visible blood vessels, and acne.

  • Avoid Broken Skin & Ulcers: Do not apply to large areas of broken skin, leg ulcers, or severe burns, as increased systemic absorption of neomycin can lead to ototoxicity (hearing damage).

  • Do Not Occlude: Do not cover treated areas with airtight dressings (occlusion) unless directed by a physician, as this dramatically increases absorption and side effect risks.

  • Potential Side Effects: Common local side effects can include burning, itching, or irritation at the application site. With prolonged or improper use, corticosteroids can cause skin thinning (atrophy), stretch marks (striae), changes in pigmentation, and increased hair growth. Neomycin can cause allergic contact dermatitis in some individuals.

  • Contraindications: Hypersensitivity to betamethasone, neomycin, other aminoglycosides, or any cream excipient. Contraindicated in viral skin infections (e.g., chickenpox, herpes), fungal infections, tuberculous or syphilitic skin conditions, and acne rosacea.

  • Pregnancy & Lactation: Use only if clearly needed and under direct medical advice.

  • Discontinuation: Long-term use should not be stopped abruptly, especially on large areas, as it may lead to a rebound flare of the original condition.

Why Trust GlaxoSmithKline (GSK)?

GSK's commitment to advancing dermatological care is embodied in products like BETNOVATE-N. Their extensive research, adherence to Good Manufacturing Practices (GMP), and focus on patient safety ensure that each 25g tube delivers a consistent, high-quality, and effective formulation. When you use a GSK product, you are utilizing a therapy backed by scientific rigor and global pharmaceutical expertise.

Conclusion

BETNOVATE-N Cream represents a rational and powerful combination for managing complex skin presentations where inflammation and infection coexist. Its targeted action provides comprehensive relief, promoting faster healing and preventing complications. However, its potency necessitates responsible use under strict medical guidance.

Final Disclaimer: This information is for educational purposes and does not replace professional medical advice, diagnosis, or treatment. Always consult your dermatologist or physician for a proper diagnosis and personalized treatment plan. Do not initiate, alter, or discontinue any medication based on information read online.

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The Undisputed Science of Creatine Monohydrate: Your Body's Phosphagen System, Amplified

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Why 300 MG of Micro-Pure, Pharmaceutical-Grade Creatine Monohydrate? The MHP Difference

The market is flooded with creatine, but not all creatine is created equal. MHP's CREATINE MONOHYDRATE 300 MG is distinguished by a commitment to purity, particle technology, and precision that sets a new industry benchmark.

  1. Pharmaceutical-Grade Purity: Unlike common commercial-grade creatine that may contain impurities like dicyandiamide, dihydrotriazine, or excess salts, MHP sources and manufactures its creatine to meet stringent pharmaceutical-grade standards. This guarantees you are ingesting 99.99% pure creatine monohydrate, free from contaminants that can cause bloating, gastrointestinal distress, or dilute efficacy. Your body utilizes what it needs without processing unnecessary impurities.

  2. Advanced Micronization Technology (300 MG Particle Size): This is the heart of the innovation. Standard creatine monohydrate has a larger, granular particle size (often 200 mesh or larger). MHP utilizes a proprietary micronization process that reduces the particle size to an ultra-fine 300 MG powder. This critical advancement yields profound benefits:

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Beyond the Basics: Comprehensive Benefits for the Dedicated Athlete

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Trestolone acetate, also known as MENT (7 alpha-methyl-19-nortestosterone), is a synthetic androgenic-anabolic steroid (AAS) derived from testosterone. It was initially developed for use in male contraception but has gained attention in the bodybuilding and performance-enhancing community due to its potent anabolic properties.

Trestolone acetate is considered to be one of the most powerful and versatile AAS available. It exhibits both androgenic and anabolic effects, making it effective for increasing muscle mass, strength, and overall athletic performance. However, it is important to note that the use of trestolone acetate for performance enhancement is considered illegal in most sports and is generally not recommended for non-medical purposes.

One of the unique characteristics of trestolone acetate is its high affinity for the androgen receptor. It binds to the receptor with a higher affinity than testosterone, resulting in enhanced anabolic effects. This leads to increased protein synthesis, nitrogen retention, and red blood cell production, all of which contribute to muscle growth and recovery.

Trestolone acetate also has a low affinity for aromatase, the enzyme responsible for converting testosterone into estrogen. This means that it has minimal estrogenic side effects, such as water retention and gynecomastia. Additionally, its androgenic properties are relatively mild, reducing the risk of androgenic side effects like acne and hair loss.

Due to its potency, trestolone acetate is typically used in lower doses compared to other AAS. It is commonly administered via injection, and the dosage and frequency depend on the individual's goals, experience level, and tolerance. It is advised to consult with a healthcare professional or an expert before considering the use of trestolone acetate or any other AAS.

Like any AAS, trestolone acetate carries potential side effects, including suppression of natural testosterone production, liver strain, cardiovascular risks, and mood changes. Therefore, it is crucial to approach its use with caution, follow proper dosage guidelines, and prioritize post-cycle therapy to help restore natural hormone production.

In conclusion, trestolone acetate is a powerful synthetic androgenic-anabolic steroid with exceptional anabolic effects and minimal estrogenic side effects. While it has gained popularity in certain circles, its use for performance enhancement is generally discouraged due to legal and health risks. It is essential to prioritize safety, consult with professionals, and be aware of potential side effects when considering the use of trestolone acetate or any other AAS.



Methenolone acetate, commonly known as Primobolan, is a synthetic anabolic androgenic steroid (AAS) that has gained popularity among athletes and bodybuilders for its unique properties. With its origins dating back to the 1960s, Methenolone acetate has become a sought-after compound for individuals looking to enhance their performance and achieve a lean and sculpted physique. In this detailed description, we will explore the various aspects of Methenolone acetate, including its chemical structure, mode of action, benefits, side effects, and its place in the world of sports and fitness.

Chemically, Methenolone acetate is derived from dihydrotestosterone (DHT) and features an added 1-methyl group, which alters its properties and makes it more resistant to metabolism in the liver. This modification allows Methenolone acetate to be orally active, making it a convenient choice for those who prefer not to use injectable steroids. The molecular formula of Methenolone acetate is C22H32O3, and it has a molecular weight of 344.50 g/mol.

Methenolone acetate exerts its effects by binding to androgen receptors in various tissues throughout the body. This interaction activates specific signaling pathways, leading to an increase in protein synthesis, nitrogen retention, and an overall improvement in muscle growth and recovery. Additionally, Methenolone acetate exhibits low androgenic activity, making it a popular choice for female athletes seeking performance enhancement without the risk of virilization.

One of the primary benefits of Methenolone acetate is its ability to promote lean muscle mass gains without excessive water retention or bloating. This characteristic makes it a preferred choice for individuals looking for quality muscle gains, especially during cutting phases or when aiming for a more defined and aesthetic physique. Methenolone acetate is often used in combination with other compounds to enhance its effects and create synergistic results.

Another advantage of Methenolone acetate is its relatively mild nature concerning side effects. Compared to other steroids, it exhibits a low risk of aromatization, meaning it does not convert into estrogen. This quality eliminates concerns related to estrogenic side effects such as gynecomastia or excessive water retention. However, it is crucial to note that Methenolone acetate can still suppress natural testosterone production, leading to potential hormonal imbalances. To mitigate this effect, individuals often incorporate post-cycle therapy (PCT) protocols to restore natural testosterone levels.

In terms of dosage and administration, Methenolone acetate is typically taken orally, in the form of tablets or capsules. The recommended dosage for men ranges from 50mg to 100mg per day, with some experienced users opting for higher doses. For women, the suggested dosage is significantly lower, usually ranging from 10mg to 25mg per day to minimize the risk of virilization. The duration of Methenolone acetate cycles varies depending on individual goals, but typical cycles last between 6 to 12 weeks.

While Methenolone acetate offers several benefits, it is essential to be aware of potential side effects. Like any AAS, Methenolone acetate can negatively impact lipid profiles, leading to a decrease in HDL (good) cholesterol and an increase in LDL (bad) cholesterol. It is crucial to monitor cholesterol levels regularly and adopt a heart-healthy lifestyle, including a balanced diet and regular exercise. Other potential side effects of Methenolone acetate include acne, hair loss (in individuals predisposed to male pattern baldness), and virilization symptoms in women.

In the world of sports and athletics, Methenolone acetate has been subject to controversy and bans due to its performance-enhancing properties. The World Anti-Doping Agency (WADA) and various sports organizations prohibit the use of Methenolone acetate and classify it as a banned substance. Athletes found to be using Methenolone acetate may face severe consequences, including disqualification, loss of medals, and even bans from future competitions.

In summary, Methenolone acetate, or Primobolan, is a synthetic anabolic androgenic steroid that offers unique benefits for individuals seeking performance enhancement and muscle growth. Its ability to promote lean muscle gains, minimal estrogenic side effects, and relatively mild nature make it a popular choice among athletes and bodybuilders. However, it is essential to approach Methenolone acetate with caution, adhering to proper dosage guidelines and understanding the potential risks and side effects associated with its use.



Title: Tamoxifen: A Comprehensive Guide to Usage, Mechanism, and Side Effects

Introduction:
Tamoxifen is a medication that has been widely used for the treatment of breast cancer for several decades. It is an important drug in the field of oncology and has played a crucial role in improving the survival rates and quality of life for many patients. This article aims to provide a detailed description of Tamoxifen, including its usage, mechanism of action, and potential side effects.

Usage:
Tamoxifen is primarily used for the treatment of hormone receptor-positive breast cancer, both in pre-menopausal and post-menopausal women. It can be administered as an adjuvant therapy after surgery, radiation, or chemotherapy, or as a first-line treatment for advanced or metastatic breast cancer. Furthermore, Tamoxifen has proven effective in reducing the risk of breast cancer in high-risk individuals, such as those with a family history of the disease or certain genetic mutations.

Mechanism of Action:
Tamoxifen exerts its effects by acting as a selective estrogen receptor modulator (SERM). It competes with estrogen for binding to estrogen receptors in breast tissue, effectively blocking the estrogen signaling pathway. This inhibitory action prevents the growth and proliferation of hormone receptor-positive breast cancer cells, ultimately leading to tumor regression. Additionally, Tamoxifen has been shown to enhance the production of certain proteins that inhibit cell growth and promote cell death, further contributing to its anti-cancer effects.

Side Effects:
While Tamoxifen is generally well-tolerated, it is important to be aware of its potential side effects. The most common side effects include hot flashes, vaginal dryness, and irregular menstrual periods in pre-menopausal women. Post-menopausal women may experience menopausal symptoms such as night sweats and mood swings. These side effects are usually mild and can be managed with symptomatic treatment or hormone replacement therapy if necessary.

Tamoxifen may also have an impact on bone health, as it can reduce bone mineral density and increase the risk of osteoporosis. Regular bone density assessments and appropriate interventions, such as calcium and vitamin D supplementation, are important for minimizing this risk. Additionally, Tamoxifen has been associated with a slightly increased risk of blood clots, which can manifest as deep vein thrombosis or pulmonary embolism. Patients on Tamoxifen should be educated about the signs and symptoms of blood clots and seek immediate medical attention if they occur.

Another important consideration is Tamoxifen's potential effect on the endometrium. It has been associated with a slightly increased risk of endometrial cancer, although this risk is outweighed by the drug's benefits in treating breast cancer. Regular gynecological examinations and monitoring for any signs of abnormal vaginal bleeding are crucial for early detection and management of endometrial changes.

It is worth noting that Tamoxifen may interact with certain medications, including selective serotonin reuptake inhibitors (SSRIs) and aromatase inhibitors. Therefore, it is important for patients to inform their healthcare providers about any other medications they are taking to avoid potential drug interactions.

Conclusion:
Tamoxifen is a vital medication in the treatment of hormone receptor-positive breast cancer. Its ability to modulate estrogen receptor signaling has been instrumental in improving outcomes for patients. While Tamoxifen is generally well-tolerated, it is essential for patients and healthcare providers to be aware of its potential side effects and take appropriate measures to minimize risks. Overall, Tamoxifen's benefits in treating breast cancer far outweigh its potential risks, making it an indispensable tool in the fight against this disease.



Unlock the Potential of Cellular Renewal with GenLabs GHK-Cu

In the sophisticated field of biochemical research, certain molecules stand out for their remarkable multifunctionality and profound influence on cellular processes. Glycyl-L-Histidyl-L-Lysine, complexed with copper—commonly known as GHK-Cu or Copper Peptide—is one such molecule. GenLabs is proud to introduce our GHK-Cu 50mg Vial, a premium-grade, lyophilized research peptide, accompanied by a dedicated vial of Bacteriostatic Water (Bac Water) for precise reconstitution. This product is meticulously manufactured under stringent controls for researchers dedicated to exploring the frontiers of tissue repair, extracellular matrix biology, and antioxidant defense mechanisms.

This complete kit represents the pinnacle of purity and convenience, designed for the exacting standards of laboratory science. It is intended for research use only in controlled laboratory settings (in-vitro) and is not for human or veterinary use.

What is GHK-Cu? The Science of a Master Signal Peptide

GHK-Cu is a naturally occurring tripeptide (Glycine-Histidine-Lysine) found in human plasma, whose levels correlate with youth and health. Its primary role is that of a master regulator and signaling molecule. When complexed with copper (Cu2+), it becomes a potent bioactive compound that influences a wide array of genes related to tissue homeostasis.

The core mechanism of GHK-Cu lies in its ability to:

  • Modulate Gene Expression: Research indicates GHK-Cu can upregulate or downregulate hundreds of genes, shifting cellular activity from a state of degeneration and inflammation to a state of repair and regeneration.

  • Promote Collagen & Glycosaminoglycan (GAG) Synthesis: It is a well-documented stimulator of key structural proteins (collagen I, III, IV) and compounds like elastin and fibronectin, which are fundamental to the integrity, firmness, and elasticity of connective tissue.

  • Exert Powerful Antioxidant and Anti-Inflammatory Actions: GHK-Cu can scavenge damaging free radicals and reduce the expression of inflammatory cytokines, thereby helping to protect cells from oxidative stress and creating a conducive environment for healing.

  • Support Cellular Migration and Remodeling: It attracts immune cells and fibroblasts to sites of need and promotes the organized remodeling of the extracellular matrix (ECM), crucial for proper tissue repair over mere scar formation.

GenLabs GHK-Cu 50mg: Uncompromising Quality for Unbiased Research

Our commitment is to provide researchers with tools of the highest integrity, ensuring that experimental results are a reflection of the compound's true biological activity, not compromised by impurities or inconsistencies.

  • High-Purity Lyophilized Powder: Each vial contains 50mg of GHK-Cu in a sterile, lyophilized (freeze-dried) form, ensuring long-term stability and potency.

  • Included Bacteriostatic Water: We provide a separate, sterile 30ml vial of Bacteriostatic Water (0.9% Benzyl Alcohol). This is essential for safe, multi-dose reconstitution, preventing bacterial growth in the solution over the research period.

  • Third-Party Verified: Every batch is analyzed by an independent, ISO-certified laboratory for ≥99% purity (via HPLC), accurate peptide content (via AAA), and absence of bacterial endotoxins and contaminants. Certificates of Analysis (CoA) are available upon request.

  • Sterile Filtered and Aseptically Packaged: The solution is sterile-filtered (0.22µ) before lyophilization, and all handling is done in an ISO Class 5 cleanroom environment to guarantee sterility.

  • Precise Batch Tracking: Fully traceable manufacturing and batch numbers ensure transparency and accountability.

Primary Research Applications & In-Vitro Study Pathways

GenLabs GHK-Cu is a versatile tool for investigating numerous biochemical pathways. Key areas of research interest include:

  1. Dermatological & Wound Healing Research:

    • Study its effects on fibroblast proliferation and collagen production in cell cultures.

    • Investigate mechanisms of re-epithelialization and ECM remodeling in wound healing models.

    • Explore modulation of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) for balanced tissue repair.

  2. Anti-Aging & Cellular Senescence Studies:

    • Examine its role in protecting cells from UV-induced damage and oxidative stress.

    • Research potential effects on telomere maintenance and senescence-associated secretory phenotype (SASP) in aged cell lines.

    • Analyze its impact on sirtuin pathways and other longevity-associated mechanisms.

  3. Anti-Inflammatory & Immunomodulation Research:

    • Assess its capacity to reduce pro-inflammatory markers (e.g., TNF-α, IL-6) in stimulated immune cell cultures.

    • Study its influence on macrophage polarization from a pro-inflammatory (M1) to a pro-healing (M2) state.

  4. Hair Follicle & Dermal Papilla Cell Research:

    • Investigate potential stimulating effects on hair follicle stem cells and dermal papilla cells in culture, exploring pathways related to hair growth cycling.

Reconstitution Protocol & Handling Guidelines

Important: This is a general guideline for research purposes. Sterile technique must be used at all times.

  1. Gather Materials: GHK-Cu 50mg vial, Bacteriostatic Water vial, alcohol wipes, sterile syringes (1ml insulin syringes are precise for measurement).

  2. Sanitize: Wipe the rubber stoppers of both vials with an alcohol swab.

  3. Reconstitute: Draw the desired volume of Bacteriostatic Water into a sterile syringe. Gently inject the solution down the side of the GHK-Cu vial to avoid aggressive agitation. Swirl gently until the powder is fully dissolved—do not shake.

  4. Storage: Once reconstituted, the solution should be stored refrigerated (2-8°C or 36-46°F) and used within a timeframe appropriate for sterile research protocols (consideration of the bacteriostatic agent's efficacy). The lyophilized powder should be stored in a cool, dry place, away from light.

Typical Research Dilutions: Concentrations used in vitro vary by cell type and assay. Common research concentrations range from 1-100 nM. Researchers must perform dose-response studies to determine optimal concentrations for their specific model system.

Why Choose GenLabs for Your Research Peptides?

  • Commitment to Science: We support the research community with reliable, high-specification biochemicals.

  • Transparency: Access to third-party CoAs for every product.

  • Rigorous QC: Our multi-point quality control system covers mass spectrometry (MS), high-performance liquid chromatography (HPLC), amino acid analysis (AAA), and sterility testing.

  • Stability Guarantee: Products are stabilized and packaged to ensure they arrive with full activity.

Disclaimer: This product is sold for laboratory research purposes only. It is not intended for human consumption, diagnostic use, or therapeutic application. It is the responsibility of the purchasing researcher to ensure compliance with all local, state, and federal regulations regarding the handling and use of research peptides. By purchasing this product, you confirm you are a qualified researcher or institution engaged in legitimate scientific inquiry.



HCG stands for Human Chorionic Gonadotropin, which is a peptide hormone naturally produced by the placenta during pregnancy. It is primarily known for its role in supporting pregnancy and fertility. However, HCG has also gained popularity as a supplement in various fields such as weight loss, bodybuilding, and hormone therapy.

HCG is composed of two subunits, an alpha subunit and a beta subunit. The alpha subunit is similar to other hormones in the body, while the beta subunit is specific to HCG. It is the beta subunit that gives HCG its unique properties and functions.

During pregnancy, HCG plays a crucial role in maintaining the production of other hormones, such as progesterone and estrogen, which are essential for the development of the fetus. It helps to sustain the corpus luteum, a temporary gland that produces these hormones until the placenta takes over the role later in pregnancy.

In the medical field, HCG is widely used to treat infertility in both men and women. In women, it stimulates ovulation, which can help with fertility issues. In men, it can increase testosterone production and improve sperm count and quality.

Outside of medical applications, HCG has gained popularity as a weight loss aid. It is often used in combination with a very low-calorie diet (VLCD). HCG is believed to help suppress appetite, promote fat burning, and preserve muscle mass during calorie restriction. However, the effectiveness of HCG for weight loss is a topic of debate, and more research is needed to establish its true efficacy.

In the realm of bodybuilding and athletic performance, HCG is sometimes used to restore natural testosterone production after a cycle of anabolic steroids. This is because anabolic steroid use can suppress the body's natural testosterone production, and HCG can help kickstart the process of restoring normal hormone levels.

It's important to note that the use of HCG as a supplement should be done under the guidance of a healthcare professional. They can provide appropriate dosages, monitor any potential side effects, and ensure its safe use.

Overall, HCG is a peptide hormone with diverse applications in medicine, fertility treatments, weight loss, and athletic performance. While it has shown promising results in certain areas, more research is needed to fully understand its benefits and risks in different contexts.



AOD 9604 (2MG VIAL) – GENLABS Premium Research Peptide

Product Name: AOD 9604 (Advanced Obesity Drug 9604)
Specification: 2mg Lyophilized Powder per Sterile Vial
Manufacturer: GENLABS
Purity: >99% (Verified by HPLC-MS)
Sequence: Tyr-hGH (177-191)

Introduction: Unveiling a Fragment of Discovery

In the cutting-edge field of metabolic and obesity research, targeted molecular tools are paramount. GENLABS is proud to offer researchers a highly refined and pure sample of AOD 9604, a synthetic peptide fragment derived from the C-terminal region (amino acids 177-191) of human Growth Hormone (hGH). This 2mg vial represents a pinnacle of peptide synthesis, providing the scientific community with a specific investigative compound designed to explore fat metabolism pathways without the proliferative or growth-promoting effects associated with the full hGH molecule.

Originally developed and patented by researchers at Metabolic Pharmaceuticals, AOD 9604 was designed to isolate the lipolytic (fat-burning) properties of hGH. For laboratory scientists, this offers a unique and focused tool to dissect the complex mechanisms of adipose tissue regulation, insulin sensitivity, and cellular metabolism. Our commitment at GENLABS is to supply this innovative peptide with uncompromising purity, consistency, and documentation, ensuring your in vitro and preclinical studies are built on a foundation of reliable, high-quality materials.

Detailed Scientific Profile and Mechanism of Action

Molecular Structure and Origin:
AOD 9604 is a modified 15-amino acid sequence (Tyr-hGH 177-191). Its structure is a synthetic replication of the fragment found in natural hGH, but with an additional tyrosine molecule to enhance stability and bioavailability in research models. This deliberate design allows it to interact with specific fat cell receptors while being metabolically "silent" in other hGH-mediated pathways.

Postulated Mechanism of Action for Research Purposes:
Laboratory studies suggest that AOD 9604 operates through a sophisticated and targeted mechanism, distinct from its parent hormone:

  1. Targeted Lipolysis: It is hypothesized to mimic the way hGH interacts with fat cells (adipocytes), specifically promoting the breakdown of stored triglycerides into free fatty acids and glycerol—a process known as lipolysis. Crucially, research indicates it may do so without stimulating the insulin-like growth factor 1 (IGF-1) axis, separating its metabolic activity from growth-promotion.

  2. Inhibition of Lipogenesis: Beyond breaking down fat, early in vitro models propose that AOD 9604 may help inhibit the conversion of carbohydrates into fatty acids (lipogenesis), particularly in the visceral fat depots. This dual-action potential makes it a compound of significant interest for metabolic syndrome research.

  3. Metabolic Rate Modulation: Some preclinical observations point to a potential role in enhancing the metabolic activity of brown adipose tissue (BAT), the "good" fat responsible for thermogenesis, thereby increasing caloric expenditure at a cellular level.

  4. Cartilage and Joint Health Pathways: Emerging, yet preliminary, research in models of tissue repair suggests AOD 9604 may stimulate chondrocyte proliferation and the synthesis of key extracellular matrix components like collagen. This opens ancillary avenues for research into musculoskeletal health and recovery.

It is imperative to note that these mechanisms are derived from scientific literature and are presented for research context. The effects of AOD 9604 in controlled laboratory settings are the primary focus for GENLABS customers.

Key Areas of Potential Research Interest

GENLABS provides AOD 9604 solely for non-human, non-clinical laboratory research. Its properties make it relevant for investigations in several scientific disciplines:

  • Metabolic Disorder Research: Studying the molecular basis of obesity, hyperlipidemia, and insulin resistance.

  • Adipocyte Biology: Investigating receptor-level interactions, fat cell differentiation (adipogenesis), and the signaling pathways that control lipolysis and lipogenesis.

  • Endocrinology & Biochemistry: Exploring the nuanced effects of hormone fragments and their receptor binding profiles.

  • Sports Science & Physiology (Preclinical): Examining models of body composition, fat reduction, and metabolic efficiency in relevant animal models.

  • Tissue Repair Studies: Preliminary research into its role in chondrogenesis and cartilage repair mechanisms.

Why Choose GENLABS for Your AOD 9604 Research?

  1. Unmatched Purity & Verification: Every batch of GENLABS AOD 9604 is synthesized to exceed 99% purity, as rigorously verified by High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). Each vial includes a unique Certificate of Analysis (CoA), detailing purity, molecular weight confirmation, and sterility.

  2. Guaranteed Sterility and Stability: The peptide is supplied as a sterile, lyophilized (freeze-dried) powder in a sealed, nitrogen-filled vial. This process ensures long-term stability, prevents oxidation, and maintains the structural integrity of the molecule until reconstitution.

  3. Precision Manufacturing: Our state-of-the-art cGMP-compliant facilities utilize solid-phase peptide synthesis (SPPS) and stringent purification processes, guaranteeing batch-to-batch consistency and accurate dosing for reproducible experimental results.

  4. Research-Grade Focus: GENLABS products are manufactured, packaged, and labeled exclusively for laboratory research use. They are not for human or veterinary consumption, diagnostic use, or any other application outside of a controlled research setting.

Storage, Handling, and Reconstitution Guidelines

  • Storage: Upon receipt, store the lyophilized vial in a cool, dry place (preferably at or below -20°C). For long-term storage (over 6 months), keeping the product frozen is essential to maintain optimal stability.

  • Reconstitution: The peptide must be reconstituted with an appropriate sterile solvent (e.g., Bacteriostatic Water). Gently swirl the vial until the powder is fully dissolved. Avoid vigorous shaking to prevent peptide denaturation.

  • Post-Reconstitution: Once reconstituted, the solution should be aliquoted and stored refrigerated (2-8°C) and used within a short timeframe, or frozen for longer stability. Multiple freeze-thaw cycles should be minimized.

Disclaimer and Compliance

GENLABS AOD 9604 is a chemical for research purposes only. This material is not a drug, dietary supplement, or cosmetic. It is not intended for human consumption, injection, or any form of personal use. It has not been evaluated or approved by the FDA or any other global regulatory body for the diagnosis, treatment, cure, or prevention of any disease or condition.

By purchasing this product, the buyer acknowledges and certifies that they are a qualified researcher affiliated with a recognized institutional or private research facility. The researcher assumes full responsibility for the safe handling, storage, and use of this material in compliance with all applicable local, state, and federal laws and regulations governing laboratory chemicals.

Order Your GENLABS AOD 9604 Today

Elevate the precision and reliability of your metabolic research with the gold standard in peptide quality. The GENLABS 2mg vial of AOD 9604 provides a potent, pure, and well-characterized tool to advance your scientific inquiries into fat metabolism and related biological processes.

Navigate complex biological questions with confidence. Add GENLABS AOD 9604 to your research protocol today.



GENLABS TESTOLONE (RAD-140) 10mg | 100 Tablets | The Next Generation of SARM Technology

Product Name: GENLABS TESTOLONE (RAD-140) 10mg Tablets
Quantity: 100 Tablets
Compound: RAD-140 (Testolone)
Dosage: 10mg per tablet
Laboratory: GENLABS


Introducing GENLABS TESTOLONE (RAD-140): Redefining Anabolic Efficiency

In the relentless pursuit of peak physical performance, body recomposition, and metabolic fortitude, the scientific community has long sought an agent that delivers the profound benefits of traditional androgens but without their significant drawbacks. Enter RAD-140 (Testolone), a revolutionary compound at the forefront of Selective Androgen Receptor Modulator (SARM) science. GENLABS is proud to present its pinnacle formulation: TESTOLONE (RAD-140) 10mg Tablets.

This is not merely a supplement; it is a precision-engineered research chemical representing a paradigm shift in how we approach anabolic signaling. Designed for the discerning researcher and disciplined athlete, GENLABS TESTOLONE offers a compelling profile of potent anabolic activity, remarkable tissue selectivity, and a favorable tolerability spectrum. Each bottle contains 100 meticulously dosed 10mg tablets, providing a full cycle for research purposes, crafted with GENLABS' unwavering commitment to purity, accuracy, and pharmaceutical-grade excellence.

What is RAD-140 (Testolone)? The Science of Selectivity

RAD-140, codenamed "Testolone," is a non-steroidal, investigational SARM originally developed for clinical applications requiring anabolic support without estrogenic or androgenic side effects in non-target tissues. Its "selective" mechanism is key to its unique profile.

Unlike traditional anabolic-androgenic steroids (AAS) that bind to androgen receptors (AR) indiscriminately throughout the body—triggering desired effects in muscle and bone but also unwanted effects in the prostate, skin (acne), and scalp (hair loss)—RAD-140 exhibits a high affinity for ARs in skeletal muscle and bone tissue. This targeted approach aims to maximize anabolic activity where it is most desired while minimizing stimulation in tissues associated with side effects. Furthermore, RAD-140 has shown no affinity for converting to estrogen via the aromatase enzyme, eliminating the risk of estrogen-related side effects like gynecomastia and water retention.

Detailed Research Parameters & Expected Observations

Primary Research Applications:

  1. Significant Lean Muscle Mass Accretion: RAD-140 is renowned for its potent anabolic capacity. In research models, it promotes a pronounced increase in lean body mass and muscular cross-sectional area. Its mechanism involves powerfully activating AR-mediated pathways in myocytes (muscle cells), leading to enhanced protein synthesis, nitrogen retention, and a profoundly anabolic environment conducive to rapid, quality tissue growth.

  2. Exceptional Strength & Power Output: Researchers consistently note dramatic improvements in strength metrics, including maximal force production, power output, and training capacity. This is attributed not only to increased muscle mass but also to RAD-140's potential positive effects on the central nervous system and neuromuscular junction, enhancing neurological drive and muscular contraction efficiency.

  3. Enhanced Fat Loss & Metabolic Rate: RAD-140 exhibits a notable ability to promote lipid metabolism and reduce adipose tissue. Its action increases basal metabolic rate (BMR) and promotes a shift in fuel utilization, encouraging the body to prioritize fat as an energy source, thereby supporting sharp, defined physiques and improved body composition ratios.

  4. Bone Density & Connective Tissue Support: As a SARM with strong affinity for bone tissue, RAD-140 demonstrates positive effects on bone mineral density (BMD) and skeletal strength. This makes it a compound of interest for research into osteopenia and overall structural integrity. Concurrently, users report enhanced joint resilience and recovery, likely due to increased collagen synthesis and anabolic support in connective tissues.

  5. Neuroprotective Properties: Emerging preclinical data indicates that RAD-140 may possess significant neuroprotective effects, potentially offering benefits for cognitive function and neuronal health. This unique attribute separates it from many other compounds in its class.

Why GENLABS TESTOLONE Stands Apart: A Commitment to Uncompromising Quality

In a market rife with inconsistency, GENLABS sets the standard. Our TESTOLONE (RAD-140) 10mg tablets are the product of relentless dedication to scientific integrity.

  • >99% HPLC-Verified Purity: Every batch is independently analyzed using High-Performance Liquid Chromatography (HPLC) to guarantee chemical purity exceeds 99%. No prohormones, no steroids, no hidden blends—just authentic, pharmaceutical-grade RAD-140.

  • Precision Dosing, Guaranteed Potency: Each tablet contains exactly 10mg of active RAD-140. Our state-of-the-art manufacturing ensures perfect dose uniformity, so research results are consistent, predictable, and reliable.

  • Pharmaceutical-Grade Tableting: We utilize advanced direct-compression tableting technology with superior excipients for optimal bioavailability, stability, and dissolution, ensuring the compound is effectively delivered for research.

  • Rigorous Third-Party Laboratory Testing: Beyond in-house QA, samples from every production run are sent to accredited, independent third-party laboratories for verification of identity, purity, and dosage. Certificates of Analysis (CoA) are available, underscoring our commitment to transparency.

  • Secure, Discrete Packaging: Your order arrives in plain, secure packaging, ensuring privacy and product integrity during transit.

Research Guidelines & Important Considerations

  • Research Subject Profile: RAD-140 is typically researched in subjects with a solid training foundation, seeking突破 in body recomposition, strength, and performance.

  • Dosage Protocol: Common research dosages for RAD-140 range from 10mg to 20mg per day, often administered in a single daily dose due to its long half-life (~20 hours). The GENLABS 10mg tablet allows for precise and flexible dosing strategies. A typical research cycle lasts 8-12 weeks.

  • Post-Cycle Therapy (PCT) Consideration: As a potent SARM, RAD-140 can cause significant suppression of endogenous testosterone production via HPTA feedback. While its side effect profile is cleaner than steroids, a comprehensive post-cycle therapy (PCT) protocol, often involving SERMs like Tamoxifen Citrate or Clomiphene Citrate, is considered essential in research to restore natural hormone function after a cycle.

  • Side Effects & Monitoring: Potential research observations may include testosterone suppression, mild lipid profile fluctuations (decrease in HDL cholesterol), and, at higher doses, rare instances of minor androgenic effects. Responsible research includes regular health marker monitoring.

GENLABS: Your Partner in Advanced Performance Research

Choosing GENLABS is choosing a partnership rooted in science, safety, and results. We empower researchers, athletes, and pioneers with the highest-quality compounds, enabling them to explore the boundaries of human performance with confidence.

Disclaimer: GENLABS TESTOLONE (RAD-140) 10mg Tablets are intended for laboratory and research use only, in vitro studies, or athletic performance research not involving human subjects. This product is not a dietary supplement, nor is it intended to diagnose, treat, cure, or prevent any disease. It is strictly for use by qualified research professionals in controlled environments. Keep out of reach of children and unauthorized personnel. By purchasing this product, you acknowledge and certify that you are a licensed researcher and understand the chemical’s intended legal use.

Unlock the next era of anabolic research. Experience the selective power of GENLABS TESTOLONE (RAD-140).



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