Product Name: GenLabs TB-500 (5mg per vial) Lyophilized Peptide. Includes 1x 5mg TB-500 vial and 1x vial of Bacteriostatic Water (Bac Water) for reconstitution.
SKU: GL-TB500-5MG
Category: Research Peptides / Tissue Repair & Recovery Compounds
Keyword Focus: TB-500 peptide, Thymosin Beta-4, tissue repair peptide, muscle recovery, tendon healing, injury rehabilitation, research peptide, GenLabs peptides.
In the rigorous world of biomedical and performance research, the quest to understand and support the body’s innate healing mechanisms is paramount. GenLabs introduces its premium TB-500 (Thymosin Beta-4) 5mg/vial, presented with bacteriostatic water for precise reconstitution. This product represents a pinnacle of purity and stability for researchers investigating the profound role of this naturally occurring peptide in cellular regeneration, inflammation modulation, and structural tissue remodeling. Meticulously synthesized and analytically verified, GenLabs TB-500 provides the reliable, high-fidelity research material necessary to explore accelerated recovery protocols, enhanced cellular resilience, and the fundamental biology of repair processes in laboratory settings.
TB-500 is a synthetic, lab-created version of the endogenous peptide Thymosin Beta-4 (Tβ4), a 43-amino-acid chain present in virtually all human cells and particularly concentrated in blood platelets, wound fluid, and regenerative tissues. Unlike fragmented or modified peptides, the TB-500 sequence is engineered to replicate the active site of the full Tβ4 molecule, which is responsible for its primary biological activities.
Its mechanism of action is multi-faceted and central to its research significance:
Actin Regulation & Cell Mobility: Tβ4’s primary molecular function is the sequestration of monomeric actin (G-actin), regulating the cell’s cytoskeletal architecture. This action directly promotes cell migration, proliferation, and differentiation. By facilitating the movement of progenitor and repair cells to the site of injury, it initiates and accelerates the healing cascade.
Angiogenesis Promotion: The peptide supports the formation of new blood vessels from existing ones (angiogenesis). This is critical for delivering oxygen, nutrients, and additional repair factors to damaged tissues, establishing a supportive microenvironment for regeneration.
Anti-Inflammatory Action: TB-500 downregulates key inflammatory cytokines (e.g., TNF-α, IL-1β, IL-6). This modulation of the inflammatory response helps control excessive or prolonged inflammation, which can be detrimental to tissue architecture and delay the later stages of healing (remodeling).
Upregulation of Matrix Metalloproteinases (MMPs) & Cell Surface Integrins: It increases the expression of enzymes that break down damaged extracellular matrix (ECM) debris and enhances cell-ECM adhesion. This dual action effectively “clears the site” and allows new, healthy tissue to be laid down more efficiently.
Keratinocyte & Collagen Production: Research indicates it supports the migration of keratinocytes for epithelial wound closure and influences the production of Type I collagen, the primary structural protein in tendons, ligaments, and skin.
Not all research peptides are created equal. GenLabs TB-500 is produced under stringent, ISO-certified conditions to ensure the integrity of your research.
≥99% Purity: Verified via High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). This minimizes the presence of impurities or truncated sequences that could confound experimental results.
Lyophilized (Freeze-Dried) Form: The peptide is provided as a sterile, stable white powder in a neutral glass vial. Lyophilization ensures long-term stability at recommended storage temperatures (below -18°C or -0.4°F for long-term storage; 2-8°C or 36-46°F for short-term).
Sterile, Non-Pyrogenic Vial: Each vial is manufactured in a cGMP-compliant facility and sealed to guarantee sterility and prevent contamination.
Included Bacteriostatic Water: Each order includes a separate vial of 0.9% Benzyl Alcohol Bacteriostatic Water. This sterile solvent contains an antimicrobial agent to prevent bacterial growth in the reconstituted solution for multi-dose research use, ensuring peptide stability post-reconstitution.
GenLabs TB-500 is intended for in vitro (cell culture) and in vivo (animal model) research to study:
Musculoskeletal Repair: Models of tendonitis, ligament strain, muscle tear, and surgically induced muscle injury. Research focuses on time-to-healing, histological analysis of collagen alignment, and restoration of tensile strength.
Cardiac Tissue Research: Investigation of post-myocardial infarction (heart attack) repair, angiogenesis in ischemic tissue, and reduction of inflammatory damage to cardiomyocytes.
Dermatological & Epithelial Studies: Wound healing models (e.g., diabetic ulcers, excisional wounds), examining rates of re-epithelialization, dermal remodeling, and scar modulation.
Neurological Exploration: Preliminary research into neurogenesis, axonal outgrowth, and recovery in models of central and peripheral nervous system injury.
Ophthalmic Research: Studies on corneal epithelial healing and repair of other ocular surface injuries.
Important Note: This is a technical guideline for qualified researchers. Aseptic technique must be used in a controlled laboratory environment.
Preparation: Sanitize the work area. Allow the TB-500 and bacteriostatic water vials to reach ambient temperature. Wear appropriate PPE.
Reconstitution: Draw the desired volume of bacteriostatic water into a sterile syringe. Gently inject the water down the side of the TB-500 vial to avoid forceful agitation. Swirl the vial gently until the lyophilized powder is fully dissolved into a clear solution. Do not shake violently.
Dosage Calculation: Concentration is researcher-dependent. Example: Adding 1ml of bacteriostatic water to a 5mg vial yields a concentration of 5mg/ml (or 5000mcg/ml). Further dilutions can be made for specific dosing volumes in research models.
Storage: Once reconstituted, the solution should be refrigerated immediately (2-8°C / 36-46°F). The inclusion of bacteriostatic water typically allows for stable use for up to 21-30 days post-reconstitution when stored correctly. For longer-term storage, aliquot and freeze at ≤ -18°C.
Integrated Solution: No need to source bacteriostatic water separately. The complete kit ensures compatibility and convenience.
Analytical Confidence: Each batch is backed by a Certificate of Analysis (CoA) accessible upon request, detailing purity, weight, and sterility.
Research-Grade Specificity: Manufactured, packaged, and labeled exclusively for laboratory research use. Not for human consumption, diagnostic, or therapeutic use.
Brand Integrity: GenLabs is committed to advancing scientific discovery by providing researchers with the most reliable and well-characterized peptide tools available.
GenLabs TB-500 (5mg/vial) is a chemical reagent for laboratory research purposes only. It is not a drug, dietary supplement, or cosmetic. This material is not intended for human or veterinary consumption, diagnosis, or treatment. It is the sole responsibility of the purchasing individual or entity to ensure that their purchase, possession, and use of this product comply with all applicable local, state, national, and international laws, regulations, and guidelines governing the procurement and use of research chemicals. The researcher assumes all risks associated with the handling and use of this product.
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